Treatment with cotrimoxazole in infants exposed to HIV but uninfected (HEU) increases resistance gene prevalence and α-diversity and decreases microbial taxonomic, functional pathway, and resistance gene β-diversity.
The prevalence of neural tube defects is 7.0 per 10,000 live births in HIV-exposed pregnancies, which is similar to the prevalence in the general population.
HIV-infected patients lose immunity to smallpox despite childhood vaccination and immune reconstitution with antiretroviral therapy.
Data published in JAMA Network Open suggest that prescribing practices of antiretroviral therapy (ART) in pregnant women living with HIV in the United States do not align optimally with national guidelines. In this prospective cohort study including data from 1867 pregnancies in 1582 women living with HIV, 49.5% were associated with prescribed ART designated as…
Starting antiretroviral therapy (ART) for HIV-infected infants within hours of birth does not seem to result in a higher proportion of infants who attain and sustain viral suppression on ART.
A substantial number of HIV infections are likely attributable to pre-existing infection with the herpes simplex virus type 2.
The researchers suggest including information about bone-healthy lifestyle in the management of PLWHIV, as well as earlier initiation of osteoporosis prophylaxis and treatment.
Drug interactions between ART and direct-acting antivirals pose a clinical challenge in patients with HIV/hepatitis C virus coinfection.
An evaluation of the FDA program to review antiretroviral drugs for use in low-resource settings, conducted by the PEPFAR, showed that the FDA’s efforts have made many HIV drugs available for use globally.
The implications of expanding HIV pre-exposure prophylaxis coverage in men who have sex with men on sexually transmitted infection epidemics vary depending on the benefit to the individual or the population.
