Persistent ALT Elevation in HIV-HBV Coinfection May Signal Coexisting Fatty Liver Disease
Patients with persistent ALT elevation despite controlled HBV should undergo evaluation for metabolic risk and fatty liver disease.
HIV/AIDS
Switch From Efavirenz to Integrase Strand Transfer Inhibitors Related to Weight Gain
Researchers studied 61 HIV-infected individuals who switched from efavirenz- to integrase strand transfer inhibitor (INSTI)-based therapies.
Darunavir Resistance Development Is Rare in HIV Treatment
Researchers evaluated the results of multiple phase 2 and phase 3 clinical trials and found that drug resistance to darunavir, an HIV protease inhibitor, is rare.
Understanding the Oncogenic Role of HIV in Burkitt Lymphoma
While the rate of certain HIV-linked non-Hodgkin lymphomas has declined since the introduction of ART, the incidence of Burkitt lymphoma has remained steady.
High-Quality TB Drugs, ART Reduce Death From Multidrug-Resistant TB in HIV
A team of investigators conducted an individual patient data meta-analysis to evaluate how treatment for tuberculosis and antiretroviral therapy affect the risk of mortality in patients with HIV and multidrug-resistant tuberculosis.
Alcohol Use in HIV Associated With Intestinal Dysbiosis, CD8+ T-Cell Dysfunction
In post-hoc analyses, researchers analyzed alcohol use data and whole-blood samples from 359 participants in the New Orleans Alcohol Use in HIV study to explore the association between intestinal leak, dysbiosis, and T cells.
Dovato Use Expanded to Include Virologically Suppressed Adults With HIV-1
Previously, Dovato was only approved for treatment-naïve adults.
Novel Immunoassay Demonstrates Predictive Utility in PrEP Adherence, HIV Protection
A novel tenofovir urine immunoassay demonstrated predictive utility and may adequately determine PrEP adherence.
Brodalumab for the Treatment of Psoriasis in Patients With HIV
A first clinical experience with brodalumab in an HIV-positive patient proves successful and may imply the utility of brodalumab in this patient group.
Efficacy of Bundled HIV, HCV Testing for People With Substance Abuse Disorders Examined
By providing bundled HIV and HCV testing, substance use disorder treatment programs may create increased awareness of infection status among people with substance abuse disorders.
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