As a result of retrospective identification of inappropriate use of antibiotics, antimicrobial stewardship is a growing area of concern and research in medicine. This was clearly demonstrated via a plethora of poster presentations on this topic at IDWeek 2019.
Polymicrobial prosthetic joint infections managed with surgical debridement, antibiotics and implant retention (DAIR) had high readmission rates and deep surgical site infections.
Two studies on hepatitis A and hepatitis B vaccination highlight opportunities to improve coverage of ≥2 doses of hepatitis A vaccine in children and hepatitis B vaccine series completion in adults.
The involvement of the biliary tract in bacteremia caused by Staphylococcus aureus may be more likely to develop in certain patients and aggressive treatment should be considered.
Bloodstream infections are common in patients who have received a solid organ transplants.
HIV treatment and virologic failure, and sustained viral response at week 12 or 24 were not different among patients who did or did not undergo a switch in their antiretroviral therapy regimen prior to DAA treatment.
A shorter course of antibiotic treatment for uncomplicated gram-negative bloodstream infections appears to be as effective as long-course antibiotic treatment.
Despite potent antiretroviral therapy, HIV-associated dementia results in significant morbidity and mortality.
Hepatitis E seropositivity is higher in older adults and may represent an increased exposure risk over time; in contrast, the opioid crisis has caused a demographic shift in hepatitis C infection, which is now a predominately millennial disease.
Data on a prefusion respiratory syncytial virus fusion glycoprotein subunit vaccine antigen strongly support this vaccine’s development as a method of preventing the virus in infants by immunizing pregnant women.
