Impact of COVID-19 Estimated on HIV, TB, Malaria Services
Disruption to services for HIV, tuberculosis, and malaria due to COVID-19 could lead to considerable loss of life in low- and middle-income countries.
Malaria
Extracellular Histones in Cerebral Malaria Linked to Blood-Brain Barrier Breakdown
Surface accumulation of parasite histones may be linked to coagulation activation and blood-brain barrier breakdown in children with cerebral malaria.
Tafenoquine Now Available for Malaria Prevention
Arakoda (tafenoquine; 60 Degrees Pharmaceuticals) has been made available in the US for the prevention of malaria in patients aged ≥18 years.
Short-Course, High-Dose Primaquine Effective for Radical Cure of P vivax Malaria
For patients with normal glucose-6-phosphate dehydrogenase activity in malaria-endemic areas where frequent relapsing strains of Plasmodium vivax are prevalent, a 7-day high-dose course of primaquine was noninferior to a 14-day course.
Suboptimal Prospects for Severe Malaria Treatment in the United States
Eli Lilly was the only pharmaceutical company providing quinidine gluconate in the United States, but in November 2017 it stopped manufacturing the drug and the remaining supplies expired.
Seven Day Primaquine Treatment Is Safe, Noninferior to 14 Day Course
In patients with malaria who have normal levels of glucose-6-phosphate dehydrogenase, 7-day primaquine was well tolerated and noninferior to 14-day primaquine.
Global Incidence, Mortality Map of Plasmodium falciparum Malaria
High-resolution maps of Plasmodium falciparum malaria informs where malaria elimination efforts should be strengthened by highlighting where burden remains high.
Malaria Incidence Higher Among African Travelers Returning to France
Significant changes may have occurred in France, in the population that developed malaria after travel in endemic areas, which implies that preventative strategies need to be adapted.
Treatment for Severe Malaria Receives Breakthrough Therapy Status
The Food and Drug Administration has granted an investigational treatment for severe malaria Breakthrough Therapy designation.
Malawi First Country to Immunize Children Against Malaria
The vaccine, called Mosquirix, was approved by the European Medicines Agency in 2015
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