Meningococcal B Vaccine Does Not Affect Carriage
4CMedB, a new multi-antigen vaccine designed to control group B meningococcal disease, had no effect on carriage of disease-causing meningococci in adolescents.
Meningitis
IDSA Meningitis Imaging Recommendations Likely to Detect Major Head CT Findings
The use of guideline recommendations from the IDSA for neuroimaging in the management of community-acquired bacterial meningitis is most likely to lead to detection of major head CT scan findings that subsequently affect clinical management.
Good Outcomes in Bacterial Meningitis and CSF Leakage
Bacterial meningitis in patients with cerebrospinal fluid (CSF) leakage has a high recurrence rate but a generally favorable outcome, according to a study published in Clinical Infectious Diseases. CSF leakage is a risk factor for bacterial meningitis. Anatomic defects of the skull caused by congenital abnormalities that allow contiguous spread of infection from ear and…
Disparity in Meningococcal Vaccine Uptake Observed Among Adolescent Patients
Factors contributing to reduced uptake of MenACWY were receipt of fewer non-MenACWY vaccines, reduced preventive care visits, and visits to nonpediatric providers.
Treatment for Cryptococcosis Gets FDA’s Orphan Drug Designation
The FDA has granted Orphan Drug designation to APX001 (Amplyx Pharmaceuticals) for the treatment of cryptococcosis.
Bexsero Vaccine Has Potential for Cross-Protection Against Gonorrhea
Meningococcal vaccine antigens may generate an immune response that recognizes gonococcal proteins.
Study to Test Efficacy of Liposomal Amphotericin for Cryptococcal Meningitis
Researchers plan to conduct a study examining whether a single high dose of liposomal amphotericin with high-dose fluconazole and flucytosine is noninferior to amphotericin.
Head or Spine Surgery Increased Risk for Streptococcus pneumoniae Meningitis
Prior head or spine surgery was associated with increased risk for Streptococcus pneumoniae meningitis outside of the postoperative period.
Increased Risk of Meningococcal Disease in Men Who Have Sex With Men
Men who have sex with men have an increased risk of meningococcal disease, however, this risk is under-ascertained and improved surveillance is needed.
Neisseria meningitidis Serogroups C and Y Vaccine Safe When Co-Administered
H influenzae type b and N meningitidis serogroups C and Y-tetanus toxoid conjugate vaccine may be safe to co-administer to infants with other scheduled vaccines.
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