Uncomplicated Appendicitis in Children: To Operate or Not to Operate?
Because outcomes of appendectomy vary by patient age, family income, and transfer status, the researchers compared outcomes in these subgroups.
Pediatrics
Effectiveness of Antipseudomonal Antibiotics for Pulmonary Exacerbation of Cystic Fibrosis
Researchers compared clinical outcomes of single vs double antipseudomonal antibiotics used to treat pulmonary exacerbations in patients with cystic fibrosis.
Use of Bronchodilators Down for Bronchiolitis Treatment in Infants
Bronchodilator therapy for the treatment of bronchiolitis in infants decreased significantly from 2010 to 2018.
Arterolane-Piperaquine-Mefloquine Noninferior to Current Therapies for Uncomplicated Malaria in Children
Investigators sought to determine the safety, tolerability, and efficacy of arterolane-piperaquine-mefloquine triple therapy vs arterolane-piperaquine and artemether-lumefantrine for uncomplicated Plasmodium falciparum malaria in children.
Pneumococcal Vaccine Associated With Steep Decline in Antibiotic Use Among Young Children in Israel
Researchers compared trends in antibiotic prescription rates during the period preceding the pneumococcal conjugate vaccine (PCV), as well as the early and late PCV periods, among Jewish vs Bedouin children.
Extended Amoxicillin-Clavulanate Not Curative for Suspected Protracted Bacterial Bronchitis Among Children
Researchers conducted a randomized controlled trial to determine the effectiveness of a 4-week course of oral amoxicillin-clavulanate in children with suspected protracted bacterial bronchitis.
Stool, Rectal Samples Detect Pathogens in Children With Isolated Vomiting
A team of investigators assessed the presence of enteropathogens in children with isolated vomiting.
Infratentorial Abnormalities Predict Ophthalmic Abnormalities in Congenital Zika Syndrome
Researchers investigated whether the presence or absence of infratentorial abnormalities in children born with clinical and radiologic features of congenital Zika syndrome was associated with ophthalmic abnormalities.
Acute Otitis Media Treatments
Acute otitis media treatment chart including select antibiotics and recommended doses.
Distinct Molecular Subtypes of RSV Bronchiolitis Identified
Four biologically and clinically meaningful endotypes identified; asthma risk higher for endotype B compared with endotype A.
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