Pneumonia Archives - Infectious Disease Advisor

Ibuprofen and Antibiotics Display Synergy Against Pseudomonas aeruginosa

By

Infectious Disease Advisor Contributing Writer

June 25, 2019

Combinations of ibuprofen with aztreonam and ceftazidime display synergistic antimicrobial activity against drug-resistant Pseudomonas aeruginosa isolates in vitro, and efficacy of ceftazidime combined with ibuprofen was shown in vivo in a murine P aeruginosa pneumonia model, according to research presented at American Society of Microbiology (ASM) Microbe 2019 held from June 20-24, 2019 in San Francisco, California. Approximately…

Pneumonia

Delafloxacin Receives FDA’s Priority Review for Community-Acquired Bacterial Pneumonia

By

Brian Park, PharmD

June 21, 2019

The sNDA is supported by data from the phase 3, double blind, DEFINE-CABP trial (N=860) which compared the safety and efficacy of Baxdela to moxifloxacin for the treatment of CABP.

Pneumonia

Testing and Antibiotic Use in Children With Community-Acquired Pneumonia

By

Infectious Disease Advisor Contributing Writer

June 18, 2019

Despite national guideline recommendations and the high prevalence of viral etiology of CAP in children, the use of antibiotics remains high.

Antibiotics, Antimicrobial Resistance

Treatment Options for Methicillin-Resistant Staphylococcus Aureus Pneumonia Evaluated

By

Brian Park, PharmD

June 18, 2019

Evidence for the treatment of MRSA pneumonia with trimethoprim-sulfamethoxazole, clindamycin, doxycycline, or minocycline was found to be based on limited data.

Pneumonia

Guiding Broad-Spectrum Antibiotic Use in Pneumonia: DRIP vs HCAP Criteria

By

Brandon May

June 3, 2019

In patients with community-onset pneumonia, the Drug-Resistance in Pneumonia (DRIP) score was better at guiding appropriate broad-spectrum antibiotic use compared with the Healthcare Associated Pneumonia (HCAP) criteria.

Bronchoscopy, man in hospital with intubation

Pneumonia

Decreasing Ventilator-Associated Pneumonia in Level I Trauma Patients

By

Britt Gambino

May 23, 2019

Performing therapeutic bronchoscopy at the time of intensive care unit admission may decrease ventilator-associated pneumonia incidence in patients with level I trauma.

Respiratory

Idiopathic Pulmonary Fibrosis Outcomes Similar With Pneumonia or Acute Exacerbation

By

Brandon May

May 22, 2019

Based on the 2016 International Working Group (IWG) diagnostic criteria for idiopathic pulmonary fibrosis (IPF), outcomes are relatively similar between patients with IPF with pneumonia and patients with an acute IPF exacerbation.

Pulmonary Medicine

Procalcitonin-Guided Care as Effective as Guideline-Based Clinical Assessment in CAP

By

Brandon May

May 9, 2019

Approaches to emergency department community-acquired pneumonia care can incorporate either guideline-based serial clinical assessment or procalcitonin-driven strategies.

Pneumonia

Safety and Efficacy of Ceftolozane/Tazobactam for Nosocomial Pneumonia

By

Bradley van Paridon

May 2, 2019

The novel combination antibacterial agent ceftolozane/tazobactam had comparable clinical and microbiologic response rates to meropenem in treating gram-negative nosocomial pneumonia.

Pneumonia

Ceftolozane/Tazobactam Noninferior to Meropenem for Nosocomial Pneumonia

By

Bradley van Paridon

May 1, 2019

A combination dose of ceftolozane/tazobactam is noninferior to meropenem for treating nosocomial pneumonia.