Corticosteroids Associated With Increased Mortality in Influenza Pneumonia
The use of corticosteroids in people with influenza pneumonia may increase rates of mortality.
Pneumonia
Poor Pneumonia Outcomes Tied to Overuse of Broad-Spectrum Antibiotics
Overuse of broad-spectrum antibiotics is associated with increased mortality and other poor outcomes in adults admitted for community-onset pneumonia.
Factors Linked to Pneumococcal Vaccination Status in Type 2 Diabetes
Patients with diabetes are at higher risk for hospitalization and mortality because of pneumococcal infection; however, uptake of vaccination remains suboptimal.
Molecular Methods Show PCV Vaccine May Reduce Colony Density, Not Acquisition
The PCV-13 demonstrated an association with the detection of low-density colonization and resulted in vaccine efficacy against colonization acquisition.
Association Between Alcohol Use Disorders and Hospital Pneumonia Outcomes
Hospitalized patients with alcohol use disorder (AUD) and community-acquired pneumonia harbor resistant organisms less often than hospitalized patients with community-acquired pneumonia (CAP) without AUD, according to a study published in JAMA Network Open. In addition, researchers noted that the higher age-adjusted mortality risk seen in patients with AUD appears to a result of differences in comorbidities,…
Characteristics of Risk Factors and Outcomes in Carbapenem-Resistant P aeruginosa
Compared with patients who have CSPA pneumonia, patients with CRPA pneumonia were more likely to be men and admitted from skilled nursing facilities and more often require mechanical ventilation.
Ibuprofen and Antibiotics Display Synergy Against Pseudomonas aeruginosa
Combinations of ibuprofen with aztreonam and ceftazidime display synergistic antimicrobial activity against drug-resistant Pseudomonas aeruginosa isolates in vitro, and efficacy of ceftazidime combined with ibuprofen was shown in vivo in a murine P aeruginosa pneumonia model, according to research presented at American Society of Microbiology (ASM) Microbe 2019 held from June 20-24, 2019 in San Francisco, California. Approximately…
Delafloxacin Receives FDA’s Priority Review for Community-Acquired Bacterial Pneumonia
The sNDA is supported by data from the phase 3, double blind, DEFINE-CABP trial (N=860) which compared the safety and efficacy of Baxdela to moxifloxacin for the treatment of CABP.
Testing and Antibiotic Use in Children With Community-Acquired Pneumonia
Despite national guideline recommendations and the high prevalence of viral etiology of CAP in children, the use of antibiotics remains high.
Treatment Options for Methicillin-Resistant Staphylococcus Aureus Pneumonia Evaluated
Evidence for the treatment of MRSA pneumonia with trimethoprim-sulfamethoxazole, clindamycin, doxycycline, or minocycline was found to be based on limited data.
Next post in Antibiotics, Antimicrobial Resistance
