Novel Pneumococcal Conjugate Vaccine Immunogenic in Phase 3 Trials
Results from PNEU-PATH demonstrated comparable immune responses following vaccination with Pneumovax 23 in both treatment groups for the 15 serotypes in V114.
Pneumonia
Pneumococcal Urinary Antigen Testing Provides Opportunity to Improve Antibiotic Stewardship
Study authors assessed pneumococcal urinary antigen testing’s use in identifying patients for broad-spectrum antibiotic de-escalation, providing an opportunity for improved antimicrobial stewardship.
Certain Hypertension Medications May Cut Deaths From Influenza, Pneumonia
Researchers linked the use of 2 hypertension drug classes to lower mortality for those hospitalized with flu and pneumonia.
Pneumomediastinum May Increase Mortality in COVID-19 Pneumonia
Pneumomediastinum, although a rare phenomenon, is more prevalent in patients with COVID-19 compared with historical patients with adult respiratory distress syndrome.
Methyl-Prednisolone Pulses May Improve COVID-19 Pneumonia Prognosis
Patients with severe COVID-19 pneumonia had improved prognosis after receiving a short course of methyl-prednisolone pulses during the second week of disease.
S Aureus ICU Pneumonia Risk Higher When Patients Are Colonized at Admission
Approximately 7% of pneumonia cases acquired in the intensive care unit can be classified as Staphylococcus aureus intensive care unit pneumonia.
Fetroja Approved for Hospital-Acquired, Ventilator-Associated Bacterial Pneumonia
The FDA has approved Fetroja® (cefiderocol; Shionogi) for the treatment of adult patients with HABP/VABP caused by susceptible Gram-negative pathogens.
Evaluating Replication Competence and Immune Response to Adenovirus Type 7 In Pediatric Populations
Researchers compared HAdV-3 with HAdV-7 replication kinetics and host response in ex vivo human lung tissue cultures.
In-Hospital Heart Failure Deaths Down With Routine Vaccinations
For patients with heart failure, influenza and pneumococcal vaccinations are associated with lower in-hospital mortality.
Invasive Potential of Pneumococcal Serotypes Post-PCV13 Implementation
The aim of this study was to evaluate the invasive disease potential of non-PCV13 serotypes after implementation of this vaccine.
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