Fetal development in uncomplicated pregnancies occurs in the absence of amniotic fluid microbiota and offspring microbial colonization starts after uterine contractions and rupture of amniotic membrane.
Further investigation into new strategies to prevent herpes simplex virus (HSV) acquisition in pregnant women and to prevent HSV transmission from mother to neonate are warranted.
The number of adverse birth outcomes was not higher with tenofovir, emtricitabine, and ritonavir-boosted lopinavir than with zidovudine, lamivudine, and ritonavir-boosted lopinavir or tenofovir, emtricitabine, and ritonavir-boosted atazanavir in HIV-infected women and their infants in the United States.
This updated Committee Opinion includes more recent data on the safety and efficacy of influenza vaccination during pregnancy, as well as recommendations for treatment and postexposure chemoprophylaxis.
About half of pregnant women with HIV infection underwent cesarean delivery between 1998 and 2013.
Findings provide an alternative explanation for virus acquisition and shedding in seroimumne pregnant women that contrasts with proposed mechanisms that argue that reactivation of persistent infection in seroimmune women leads to infection and virus shedding.
Women in the United States with uncomplicated malaria during the first trimester of pregnancy should be treated with the currently recommended options of either mefloquine or quinine plus clindamycin. However, when neither of these options is available, artemether-lumefantrine should be considered for treatment.
Researchers assessed the differential risk of acquiring HIV-1 infection across reproductive stages by calculating per-coital-act risk for each stage and comparing with nonpregnant times.
Researchers estimated this risk among pregnant women with symptomatic Zika virus infection in French territories in the Americas.
Maternal receipt of influenza and tetanus toxoid, reduced diphtheria toxoid, and Tdap vaccines is not associated with infant hospitalization or death.
