No Benefit With Tocilizumab in COVID-19 Pneumonia Trial
A phase 3 study of tocilizumab (Actemra®) for the treatment of hospitalized patients with severe COVID-19 pneumonia did not meet its primary and key secondary end points.
Respiratory
Latino Communities at Higher Risk for COVID-19
Factors linked to structural racism and social determinants of health are associated with an increased risk for COVID-19 in Latino communities.
Young Children Have Higher Amounts of SARS-CoV-2 RNA
Young children with mild-to-moderate COVID-19 have higher amounts of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) viral RNA in their nasopharynx than older children and adults.
DNA-Based Therapy Gets Orphan Drug Status for Recurrent Respiratory Papillomatosis
The FDA has granted Orphan Drug designation to INO-3107, a DNA plasmid immunotherapy, for the treatment of recurrent respiratory papillomatosis, a rare disease caused by human papillomavirus types 6 and 11 infections.
BTK Inhibition May Counter Hyperinflammatory Response Associated With Severe COVID-19
In this study, emergency, unregistered use of acalabrutinib was available to patients hospitalized with advanced COVID-19 in accordance with the WHO MEURI guidelines.
Infection May Increase Risk for Early Stroke Recurrence
Infection may be associated with an increased risk for early stroke recurrence in hospitalized patients with acute ischemic stroke.
Nirsevimab Injection Cuts RSV-Linked Infections in Preemies
Nirsevimab prevents respiratory syncytial virus (RSV)-associated lower respiratory tract infections in healthy preterm infants, while maternal RSV fusion (F) protein nanoparticle vaccination did not meet the prespecified criterion for efficacy.
Utility of Nasal/Throat vs Nasopharyngeal Swabs in COVID-19 Testing Examined
Both nasal/throat and nasopharyngeal swabs demonstrated similar sensitivity when testing healthcare workers with symptoms of COVID-19.
Depression, Anxiety May Be Signs That COVID-19 Is Attacking Brain
Depression and anxiety exhibited in COVID-19 patients may be a sign that the virus impacts the central nervous system.
Characteristics of Hyperglycemic Emergencies in COVID-19
COVID-19 is associated with hyperglycemic emergencies, particularly in patients with existing type 2 diabetes and of African ethnicity.
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