High Cortisol Observed in Children With Acute Illnesses, No Glucocorticoid Deficiency
Researchers assessed variations in cortisol concentrations among children and adolescents with acute illnesses and no history of glucocorticoid deficiency.
Septic Shock
Mortality Increased for Carbapenem-Resistant Infections Diagnosed via Blood Cultures
Investigators assessed factors associated with 90- and 365-day mortality among veterans infected carbapenem-resistant Acinetobacter baumanii and carbapenem-resistant Pseudonomas aeruginosa.
Kidney Stress Biomarkers May Improve Severity Grading in Acute Kidney Injury
Tissue inhibitor of metalloproteinases 2 (TIMP-2) and insulinlike growth factor binding protein 7 (IGFBP7) could be used for AKI staging.
COVID-19 Increases Mortality Risk in Patients Hospitalized With Sepsis
Researchers compared clinical characteristics and outcomes among patients hospitalized with sepsis who were positive vs negative for COVID-19 infection.
Association Between Delayed Antibiotic Administration and Risk for Septic Shock
Investigators conducted a study to determine whether early antibiotic administration decreases the risk for progression to septic shock among patients with suspected sepsis.
Incidence of Septic Shock in Patients With Chronic Liver Disease Admitted to the Intensive Care Unit for Treatment of Candidemia
Investigators sought to identify factors associated with septic shock development and 30-day mortality in patients admitted to an intensive care unit for treatment of candidemia.
Outcomes of Empiric Antibiotic Therapy With Adjunctive Gentamicin in Patients With Septic Shock
Investigators conducted a study to determine whether empiric antibiotic therapy with adjunctive gentamicin improves outcomes in patients with septic shock admitted to the intensive care unit.
Machine Learning Estimates Treatment Effect of Corticosteroids in Septic Shock
The researchers’ objective was to determine whether machine learning-derived estimated individual corticosteroid therapy effect yields better results than treat all or treat no one strategies in adult patients with septic shock.
S aureus Bloodstream Infection Linked to Risk for Myocardial Infarction
Investigators analyzed a potential link between community-acquired Staphylococcus aureus bloodstream infection and increased short-term risk for myocardial infarction, which is associated with subsequent mortality.
Presenting With Vague Symptoms May Increase Septic Shock Mortality Risk
A large proportion of patients with septic shock but who present to the ED with vague symptoms not specific to infection have a significantly higher mortality rate than those with symptoms that are explicit to an infection.
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