Best Approach to Reduce Surgical Site Infections Before Colorectal Surgery
Mechanical bowel preparation with oral antibiotics may be the best approach to reduce surgical site infections in patients undergoing colorectal surgery.
Skin Infections
Refinement of Remote Postoperative Monitoring With Wound Photography Is Needed
Wound photography increased specificity and surgeon confidence, and can facilitate online postoperative wound assessment.
Dundee Severity Classification Improves Management of Patients With Cellulitis
The Dundee classification can predict mortality risk in clinical settings to determine which patients can be managed with oral or IV therapy.
Topical Antibacterial Agent Effective for Treatment of Impetigo
Investigators examined tolerability, effectiveness, and safety profile of topical antibacterial agent ozenoxacin in adults and children with impetigo.
6-Week Antibiotic Treatment Effective for Spinal Surgery Site Infections
Six-week antibiotic treatment is sufficient for early, spinal surgery site infections.
Delafloxacin Equally Effective as Vancomycin/Aztreonam for Acute Bacterial, Skin Suture Infections
Treatment with intravenous and oral delafloxacin, a fluoroquinolone antibiotic with gram-negative and gram-positive activity, was comparable to vancomycin/aztreonam in improving clinical signs and symptoms in acute bacterial and skin structure infections.
Omadacycline Approved for Community-Acquired Bacterial Pneumonia, Skin Infections
The approval was based on Phase 3 data from 2 studies in ABSSSI, where treatment with Nuzyra was compared with linezolid, and 1 study in CABP comparing Nuzyra with moxifloxacin. Across all 3 trials, Nuzyra was found to be effective and generally safe and well-tolerated.
Risk Assessment Reduces Length of Hospital Stay, Costs in Patients who Inject Drugs
A 9-point risk assessment (IVAT) identified persons with a history of injection drug use (IDU) safe for discharge and reduced the mean length of hospital stay (ALOS) by 20 days and total direct cost by 33%.
FDA Gives MRX-I QIDP, Fast Track Status for Acute Bacterial Skin Infections
The structure of contezolid was designed to potentially reduce the risk of hematological toxicity associated with this class of antibiotics.
ALT-70 Model Provides Accurate Diagnosis of Lower Extremity Cellulitis
The widespread implementation of ALT-70 into clinical practice may help decrease misdiagnosis rates of lower-extremity cellulitis.
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