Switch From Efavirenz to Integrase Strand Transfer Inhibitors Related to Weight Gain
Researchers studied 61 HIV-infected individuals who switched from efavirenz- to integrase strand transfer inhibitor (INSTI)-based therapies.
Treatments
Updates and Challenges for WHO Antibiotic Targets
Investigators reviewed patterns of antibiotic consumption in each of the WHO Access, Watch, and Reserve (AWaRe) categories over a span of 15 years and documented changes.
Darunavir Resistance Development Is Rare in HIV Treatment
Researchers evaluated the results of multiple phase 2 and phase 3 clinical trials and found that drug resistance to darunavir, an HIV protease inhibitor, is rare.
Prior Care Experiences Determine Antibiotic Prescribing for Future Acute Respiratory Illness
One potential driver of high antibiotic prescribing rates for acute respiratory infections is patient’s prior care experiences.
Safety, Efficacy of 8-Week Glecaprevir/Pibrentasvir for Treatment-Naive HCV Examined
Eight weeks of treatment with glecaprevir/pibrentasvir is both efficacious and well tolerated in treatment-naive patients with HCV.
Updated CDC Guidance for Healthcare Personnel With Potential Exposure to HCV
New CDC guidelines recommend a test-and-treat approach for healthcare personnel who may have been exposed to acute hepatitis C virus infection at work.
Benefits of FilmArray Meningitis/Encephalitis Panel in CNS Infection Management
Use of the FilmArray ME panel significantly reduced the treatment duration, length of hospital stay, and total hospital cost associated with pediatric CNS infection.
Invasive Aspergillosis Superinfection Possible in Symptomatic COVID-19
Critically ill patients hospitalized with COVID-19 — particularly those who develop ARDS — may also experience an opportunistic aspergillosis superinfection.
Clinical Practice Guideline: Treatment of Nontuberculous Mycobacterial Pulmonary Disease
New clinical practice guidelines for the treatment of nontuberculous mycobacterial pulmonary disease were published by leading respiratory medicine and infectious disease societies.
Reduced Hospitalization Among People With Diabetes With Multi-Season Influenza Vaccination
Influenza hospitalizations were decreased among people with diabetes when vaccines were received in multiple influenza seasons.
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