Pharmacy Practice Managers Report Frequent Drug Shortages
More than one-third of respondents reported no administrative methods for responding to shortages.
Treatments
Pegylated Interferon α-2b Plus Ribavirin Effective for HCV Genotypes 2, 3
Investigators evaluated the real-life efficacy of pegylated interferon α-2b with ribavirin in treatment-naive patients with chronic genotypes 2 or 3 hepatitis C virus infection.
Moxifloxacin Not Superior to Ethambutol for Recurrent Tuberculosis
Replacing ethambutol with moxifloxacin has not shown efficacy in tuberculosis treatment success in an 8-week trial.
Quantifying Adherence to Mucormycosis Treatment Guidelines in Patients With Hematologic Malignancies
Adhering to mucormycosis treatment guidelines may be difficult for physicians because of the complexity of the disease.
Intermittent Vancomycin Infusion Subtherapeutic Compared With Continuous Dosing
Continuous infusion of vancomycin, compared with intermittent infusions, was linked to earlier and improved attainment of target concentrations in infants.
Noninvasive Biomarker of Variceal Bleeding in HCV Cirrhosis
Although hepatic vein pressure gradient measurement is an accurate method for evaluation of portal HTN, this technique is invasive and not widely available.
Early ART in HIV Possible Key to Dolutegravir Monotherapy Success
Dolutegravir monotherapy was noninferior to combination antiretroviral therapy (cART) in patients who started cART during primary HIV infection.
Single-Dose Tafenoquine Effective in Preventing Relapse of P vivax Malaria
Compared with placebo, single-dose tafenoquine significantly lowered risk for Plasmodium vivax malaria relapse at 6 months.
Practices Vary in Treating Adult Staphylococcus aureus Bacteremia
Practices vary among clinicians in diagnosing and managing Staphylococcus aureus bacteremia in adults.
CP101 Designated Breakthrough Tx for Recurrent C difficile Infection
The FDA has granted Breakthrough Therapy designation to CP101 for the treatment of patients with recurrent Clostridium difficile.
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