Single-Dose Tafenoquine Effective in Preventing Relapse of P vivax Malaria
Compared with placebo, single-dose tafenoquine significantly lowered risk for Plasmodium vivax malaria relapse at 6 months.
Treatments
Practices Vary in Treating Adult Staphylococcus aureus Bacteremia
Practices vary among clinicians in diagnosing and managing Staphylococcus aureus bacteremia in adults.
CP101 Designated Breakthrough Tx for Recurrent C difficile Infection
The FDA has granted Breakthrough Therapy designation to CP101 for the treatment of patients with recurrent Clostridium difficile.
Treating Shingles Does Not Reduce Increased Risk for Stroke
The risk for stroke is significantly increased after the appearance of shingles, despite adequate antiviral therapy and administration of the shingles vaccine.
Sofosbuvir-Velpatasvir Safe and Effective for Some Patients With Chronic HCV
Sofosbuvir-velpatasvir administered for 12 weeks is efficacious and safe for Asian patients with chronic HCV.
Cardiovascular Disease Events and Statin Eligibility in Patients With HIV
More patients with HIV who were not recommended for statin therapy experienced cardiovascular disease events compared with a control group.
DPP-4 Inhibition May Reduce Atherogenesis in HIV
Treatment with sitagliptin had no effect on soluble CD14 when given to participants with virally suppressed HIV infection.
Corticosteroid Use Reduces 28-Day Mortality in Sepsis
The administration of corticosteroids in patients with sepsis may be associated with significant improvement in patient outcomes.
Ledipasvir-Sofosbuvir Treatment for Chronic Hepatitis C Virus Infection
Ledipasvir-sofosbuvir treatment for chronic HCV infection may be efficacious, safe, and tolerable for HCV genotype 1 and 4.
Study to Test Efficacy of Liposomal Amphotericin for Cryptococcal Meningitis
Researchers plan to conduct a study examining whether a single high dose of liposomal amphotericin with high-dose fluconazole and flucytosine is noninferior to amphotericin.
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