Effect of HIV Pretreatment Drug Resistance on Virologic Outcomes
Dual-class pretreatment drug resistance to first-line tenofovir/emtricitabine/efavirenz regiment may be associated with poorer virologic suppression.
Treatments
Combining Corticosteroids and Antibiotics May Be Cost-Effective in CAP
Treating severe community-acquired pneumonia with a combination of corticosteroids and antibiotics may be a cost-effective strategy.
Voriconazole-Resistant Invasive Aspergillosis Associated With Higher Mortality
Patients with voriconazole-resistant invasive aspergillosis have a higher mortality rate compared with patients with voriconazole-susceptible infection.
Early Benznidazole Treatment Improves Outcomes in Chagas Disease
Benznidazole treatment during the early phases of chronic Chagas disease infection reduced parasitemia significantly.
Influenza Point-of-Care Tests Influence Patient Outcomes
Point-of-care testing for influenza has a role persons with influenza-like illnesses, particularly in emergency departments and during influenza epidemics, but tests are not a substitute for clinical assessment.
Isavuconazole Not Noninferior to Caspofungin for Invasive Candida Infections
Isavuconazole did not demonstrate noninferiority compared with caspofungin in the primary treatment of proven candidemia or invasive candidiasis.
Management of Mycobacterium chimaera Outbreak From Heater-Cooler Units
There is currently a global outbreak of disseminated Mycobacterium chimaera related to the widely used surgical device LivaNova 3T heater-cooler unit contamination.
Novel H pylori Eradication Therapy Effective in Phase 3 Trial
The ERADICATE Hp2 trial enrolled 455 dyspepsia patients at 55 sites across the US and randomized them to receive 4 capsules, 3 times daily, of either Talicia or the active comparator, for 14 days.
Topical 15% Paromomycin-Aquaphilic Effective For New World Leishmaniasis
Treatment for cutaneous leishmaniasis caused by Leishmania braziliensis, using 15% paromomycin-Aquaphilic, was superior to a negative vehicle control.
Biologic Agents Used to Treat Patients With Psoriasis and HIV Infection
Investigators evaluated the safety and effectiveness of conventional therapy with biologic immunosuppressive drugs to treat patients with HIV infection and psoriasis.
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