Treatments Archives - Page 3 of 40 - Infectious Disease Advisor

Mycoses

Toenail Onychomycosis: Treatment Options Evaluated

By

Cassandra Pardini, PharmD

June 3, 2019

A total of 26 RCTs with 8136 patients were included in this network meta analysis.

Probiotics are often used as an adjunct or nonpharmacological approach to treating various forms of arthritis, but studies have shown mixed results. A 12-week study assessing the effect of an orally administered probiotic on disease activity, fatigue, quality of life, and intestinal symptoms in patients with active SpA demonstrated no significant benefit over placebo.16 In contrast, a study assessing 8 weeks of Lactobacillus casei 01 supplementation in patients with RA showed improvements in disease activity and inflammatory status versus placebo.17 A major challenge with studying probiotics is the complexity of selecting the strains and formulations most likely to have a beneficial impact on the microbiome of the arthritis type studied. Furthermore, sufficient randomized clinical trials to guide clinical practice are lacking. Until more definitive data are available, decisions on probiotics are likely to continue to be guided by anecdotal evidence. Photo credit: MicroScape / Science Source

GI Illness

Efficacy of Lactobacillus reuteri for Acute Gastroenteritis in Children

By

Infectious Disease Advisor Contributing Writer

May 29, 2019

Among children under age 5 years with acute gastroenteritis, Lactobacillus reuteri DSM 17938 as an adjunct to rehydration therapy did not reduce the duration of diarrhea compared with placebo.

Sexually Transmitted Diseases

Gentamicin Found Inferior to Ceftriaxone for Gonorrhea Treatment

By

Zahra Masoud

May 28, 2019

Ceftriaxone remains the superior first-line treatment for gonorrhea compared with gentamicin.

Skin Infections

Comparison of Ivermectin and Permethrin for Scabies

By

Infectious Disease Advisor Contributing Writer

May 28, 2019

Investigators sought to determine whether the use of ivermectin in patients with scabies leads to improved clinical and safety outcomes compared with permethrin.

Respiratory

Efficacy Evaluation for Initial Maintenance Therapy in Chronic Pulmonary Aspergillosis

By

Sweta Gupta

May 15, 2019

Oral voriconazole may be more effective than oral itraconazole for initial maintenance therapy in patients with chronic pulmonary aspergillosis, according to a study published in Clinical Infectious Diseases.1 Currently, there are 4 oral anti-Aspergillus agents available (itraconazole, voriconazole, posaconazole, and isavuconazole) and while various studies have evaluated treatments for chronic pulmonary aspergillosis with itraconazole and…

Treatments

Rituximab-Related Serious Infections Unlikely in Multiple Sclerosis

By

Natasha Priya Dyal, MD

May 7, 2019

Serious infections related to treatment with rituximab in patients with multiple sclerosis are rare and successfully resolvable.

Practice Management

Pharmacy Practice Managers Report Frequent Drug Shortages

April 12, 2019

More than one-third of respondents reported no administrative methods for responding to shortages.

Hepatitis

Pegylated Interferon α-2b Plus Ribavirin Effective for HCV Genotypes 2, 3

By

Hannah Dellabella

April 15, 2019

Investigators evaluated the real-life efficacy of pegylated interferon α-2b with ribavirin in treatment-naive patients with chronic genotypes 2 or 3 hepatitis C virus infection.