Cabenuva Approval Expanded to Include Adolescents With HIV
The expanded approval was supported by data from studies in the adult population and by data from an interim analysis of the phase 1/2 MOCHA study.
Treatments
Safety, Efficacy of Artemether-Lumefantrine Plus Amodiaquine for Uncomplicated Malaria
Researchers evaluated first-line treatment with arthemether-lumefantrine plus amodiaquine in patients with uncomplicated Plasmodium falciparum malaria infection living in areas with an increased prevalence of multidrug-resistant parasites.
PreHevbrio Now Available for Adult Hepatitis B Vaccination
The approval was based on data from two phase 3 studies, which compared the safety and immunogenicity of PreHevbrio to Engerix-B in adults.
Safety, Outcomes of Nifurtimox in Patients With American Trypanosomiasis (Chagas Disease)
Researchers from the Centers for Disease Control and Prevention assessed the use of nifurtimox for the treatment of patients with American trypanosomiasis (Chagas disease).
Effect of Dolutegravir/Lamivudine on Inflammatory Biomarkers in People With HIV
Researchers conducted a systematic review to assess the effect of dolutegravir plus lamivudine on inflammatory and atherogenesis biomarkers in people with HIV infection.
Ivermectin Effect in COVID-19 Varies With Strongyloidiasis Prevalence
In trials of ivermectin as a treatment for COVID-19, the relative risk of mortality varies with strongyloidiasis prevalence.
Meropenem Plus Clavulanate and Rifampin for Treatment of Drug-Resistant TB
Investigators evaluated the 14-day bactericidal activity of various doses of meropenem, with or without rifampin, in patients being treated for pulmonary tuberculosis.
Effect of Baloxavir Marboxil vs Oseltamivir on Familial Influenza Transmission
Researchers compared the incidence of intra-familial influenza transmission after treatment of the first family member with baloxavir marboxil vs oseltamivir.
Outcomes of Concomitant Bedaquiline and Delamanid in Patients With Multidrug-Resistant Tuberculosis
Researchers evaluated the safety, effectiveness, and cardiotoxity risk associated with concomitant treatment with bedaquiline and delamanid in patients with multidrug-resistant tuberculosis infection.
Long-COVID Symptoms and Novel Enhanced External Counterpulsation Therapy
A retrospective study was conducted to determine if enhanced external counterpulsation is an effective therapy for long-COVID.
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