Sofosbuvir-Velpatasvir Safe and Effective for Some Patients With Chronic HCV
Sofosbuvir-velpatasvir administered for 12 weeks is efficacious and safe for Asian patients with chronic HCV.
Treatments
Cardiovascular Disease Events and Statin Eligibility in Patients With HIV
More patients with HIV who were not recommended for statin therapy experienced cardiovascular disease events compared with a control group.
DPP-4 Inhibition May Reduce Atherogenesis in HIV
Treatment with sitagliptin had no effect on soluble CD14 when given to participants with virally suppressed HIV infection.
Corticosteroid Use Reduces 28-Day Mortality in Sepsis
The administration of corticosteroids in patients with sepsis may be associated with significant improvement in patient outcomes.
Ledipasvir-Sofosbuvir Treatment for Chronic Hepatitis C Virus Infection
Ledipasvir-sofosbuvir treatment for chronic HCV infection may be efficacious, safe, and tolerable for HCV genotype 1 and 4.
Study to Test Efficacy of Liposomal Amphotericin for Cryptococcal Meningitis
Researchers plan to conduct a study examining whether a single high dose of liposomal amphotericin with high-dose fluconazole and flucytosine is noninferior to amphotericin.
Antibiotic Prescribing for CAP May Differ in Pediatric Specialty Hospitals
Compared with those at children’s hospitals, children receiving CAP care at other hospital types are less likely to be treated as per national guidelines.
Tafenoquine Appears Safe and Effective for Prevention of Malaria
Chemoprophylaxis with tafenoquine is safe and effective for preventing malaria in healthy non-immune individuals challenged with blood stage P falciparum.
Antiretroviral Resistance Testing in People With HIV May Not Be Beneficial
Antiretroviral drug resistance testing may not benefit people who have HIV, specifically in terms of mortality risk and disease progression.
Effect of HIV Pretreatment Drug Resistance on Virologic Outcomes
Dual-class pretreatment drug resistance to first-line tenofovir/emtricitabine/efavirenz regiment may be associated with poorer virologic suppression.
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