Mutation That Helps Coronavirus Evade Vaccines Showing Up in British Variant
Worrisome mutation known as E484K appears to have arisen coronavirus variant samples in the United Kingdom.
Vaccines
Pfizer-BioNTech: COVID-19 Vaccine Trial in Pregnant Women Begins; New Storage Data Submitted to FDA
The randomized, placebo-controlled, observer-blind study is evaluating the safety, tolerability, and immunogenicity of BNT162b2 in approximately 4000 healthy pregnant women aged 18 years and older who are 24 to 34 weeks’ gestation.
ACIP: 2021 Child and Adolescent Immunization Schedule Updates
Fewer childhood vaccines have been administered due to a decline in outpatient pediatric visits resulting from the COVID-19 pandemic.
EU Regulator Approves Oxford-AstraZeneca COVID-19 Vaccine
The Oxford-AstraZeneca COVID-19 vaccine is added to those made by Pfizer and Moderna, which have already been approved in the EU.
Merck Ends Development of Two COVID-19 Vaccine Candidates
While both candidates were found to be generally well tolerated, findings showed immune responses that were inferior to those seen after natural infection or those reported with other COVID-19 vaccines.
Moderna Wants to Increase Number of Doses in COVID-19 Vaccine Vials
The FDA is expected to make a decision on whether to allow Moderna to increase the number of doses in its vials of COVID-19 vaccine.
60% Receiving COVID-19 Vaccine in US Are Non-Hispanic Whites
Research published by the CDC found that of the people who received their first dose of the COVID-19 vaccine, the majority were women and non-Hispanic Whites.
Phase 3 Study Evaluating Ravulizumab for COVID-19 Paused
The open-label, controlled study enrolled adults hospitalized with COVID-19 and severe pneumonia, acute lung injury or acute respiratory distress syndrome.
FDA Fast Tracks Brilacidin for COVID-19 Treatment
Brilacidin is a first-in-class host defense protein mimetic.
AstraZeneca’s COVID-19 Vaccine Prevents Severe Disease, May Cut Transmission
AZD1222 utilizes a replication-deficient chimpanzee adenovirus to deliver a severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) protein to induce a protective immune response.
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