Phase I Trial Of An Adenovirus Vector Vaccine for Zika Virus Shows High Immunogenicity And Safety
Researchers recruited a group of 100 healthy adult volunteers to assess safety and reactogenicity outcomes of the Ad26.ZIKV.001 Zika vaccine.
Zika Virus
Zika Virus Transmission Correlated with Risky Sexual Behavior in Men
Researchers used a retrospective survey to associate sexual behavior during the Zika virus epidemic to better understand the disease burden of sexually transmitted Zika virus.
Optimization of Zika Virus Vaccination Schedule
As a ZPIV vaccine had proved to be well tolerated and immunogenic at up to 8 weeks of follow-up, investigators evaluated the safety and immunogenicity of ZPIV at up to 52 weeks of follow-up using a standard or accelerated vaccination schedules.
Climate Change Ushers in Era of Uncertainty for Infectious Diseases
A high frequency of climate-change associated severe weather events have created an increased human-to-human transmission risk for novel diseases.
Neuroimaging Abnormalities Common in Zika-Exposed Infants
Infants exposed to Zika virus commonly had neuroimaging abnormalities on computed tomography and/or magnetic resonance imaging scans.
Investigational Zika Vaccine Gets Fast Track Status
An investigational mRNA vaccine to prevent Zika virus infection has been granted Fast Track designation by the FDA.
Characterization of Neurologic Manifestations in Zika Virus Infection
Neurologic manifestations associated with the Zika virus encompass a large group of clinical neurologic manifestations. Researchers found a modified Rankin scale score may help identify the risk for mechanical ventilation in certain patients with the virus.
Diagnostics in Patients At Risk for Both Dengue and Zika Infection
The CDC has summarized present and updated guidelines on dengue and Zika virus diagnostic testing in patients with a clinically compatible illness who live in or recently traveled to an endemic area.
Suboptimal Performance of Two Commercial Zika Diagnostic Tests
The performance of 2 commercial serologic tests for diagnosing Zika virus was deemed suboptimal, according to data published in Emerging Infectious Diseases. Investigators evaluated both the Euroimmun and Dia.Pro serologic tests for detection of Zika virus immunoglobulin (Ig)M and IgG using a panel of 199 samples from a flavivirus endemic region, 90 of which were…
First Zika Diagnostic Test Cleared for Marketing in the US
The FDA has cleared the ZIKV Detect 2.0 lgM Capture ELISA (InBios) for testing of Zika virus immunoglobulin antibodies in blood.
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