Neurologic Manifestations of Zika Virus Infection: What We Know So Far
Jonathan Miner, MD, PhD, and Karin Nielsen-Saines, MD, MPH, discuss the latest insights about neurologic complications of ZVI and knowledge gaps that still exist in this field.
Zika Virus
Examining Pregnant Women’s Attitudes Toward a Zika Vaccine Trial
Pregnant women placed a high premium on clinical evidence when considering whether or not to participate in a hypothetic clinical trial of a Zika virus vaccine.
Engineered Resistance to Zika Virus in Transgenic Mosquitoes
Engineered mosquitoes may express a polycistronic cluster of synthetic RNA designed to be resistant to the Zika virus genome.
Prior Dengue Infection May Protect Against Symptomatic Zika in Children
Children with prior dengue virus infection had a decreased risk of being symptomatic when infected with Zika virus.
Neurologic and Ocular Malformations Associated With Zika Virus Infection
Researchers examined a full range of data on neurological complications in newborns and infants born to women infected with Zika virus.
Zika Vaccine Cost-Effective for Young Adults and Childbearing-Age Women
The most cost-effective means of decreasing transmission of Zika virus is administration of the vaccine to young adults and women of childbearing age.
Targeted Blood Donor Screening for Zika More Cost Effective vs Universal
Screening the donated blood supply for Zika virus is only cost-effective during the high mosquito season in Puerto Rico, but not in the United States.
Sequential Prenatal, Postnatal Neuroimaging in Zika-Exposed Infants
Sequential neuroimaging indicated that prenatal and postnatal ultrasonography may identify Zika virus-related brain injury in most patients.
Association of Hydrocephalus With Congenital Zika Syndrome
Evidence that hydrocephalus is a complication in at least a proportion of patients with congenital Zika syndrome has been published in JAMA Neurology.
Biomarkers Associated With Zika Virus Fetal Abnormalities
An analysis of 69 cytokines found 3 specific chemokines that are specifically associated with symptomatic Zika virus infection during pregnancy.
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