Investigational Zika Vaccine Gets Fast Track Status
An investigational mRNA vaccine to prevent Zika virus infection has been granted Fast Track designation by the FDA.
Zika Virus
Characterization of Neurologic Manifestations in Zika Virus Infection
Neurologic manifestations associated with the Zika virus encompass a large group of clinical neurologic manifestations. Researchers found a modified Rankin scale score may help identify the risk for mechanical ventilation in certain patients with the virus.
Diagnostics in Patients At Risk for Both Dengue and Zika Infection
The CDC has summarized present and updated guidelines on dengue and Zika virus diagnostic testing in patients with a clinically compatible illness who live in or recently traveled to an endemic area.
Suboptimal Performance of Two Commercial Zika Diagnostic Tests
The performance of 2 commercial serologic tests for diagnosing Zika virus was deemed suboptimal, according to data published in Emerging Infectious Diseases. Investigators evaluated both the Euroimmun and Dia.Pro serologic tests for detection of Zika virus immunoglobulin (Ig)M and IgG using a panel of 199 samples from a flavivirus endemic region, 90 of which were…
First Zika Diagnostic Test Cleared for Marketing in the US
The FDA has cleared the ZIKV Detect 2.0 lgM Capture ELISA (InBios) for testing of Zika virus immunoglobulin antibodies in blood.
Factors Associated With Poor Motor Function in Congenital Zika Syndrome
Factors found to affect motor function in congenital Zika syndrome were the presence of severe malformations of cortical development and small head circumference at birth.
Neurologic Manifestations of Zika Virus Infection: What We Know So Far
Jonathan Miner, MD, PhD, and Karin Nielsen-Saines, MD, MPH, discuss the latest insights about neurologic complications of ZVI and knowledge gaps that still exist in this field.
Examining Pregnant Women’s Attitudes Toward a Zika Vaccine Trial
Pregnant women placed a high premium on clinical evidence when considering whether or not to participate in a hypothetic clinical trial of a Zika virus vaccine.
Engineered Resistance to Zika Virus in Transgenic Mosquitoes
Engineered mosquitoes may express a polycistronic cluster of synthetic RNA designed to be resistant to the Zika virus genome.
Prior Dengue Infection May Protect Against Symptomatic Zika in Children
Children with prior dengue virus infection had a decreased risk of being symptomatic when infected with Zika virus.
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