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Treating Acute Urinary Tract Infection in Postmenopausal Women
Expert perspective on management and treatment of acute urinary tract infections in postmenopausal women.
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Treating Shingles Does Not Reduce Increased Risk for Stroke
The risk for stroke is significantly increased after the appearance of shingles, despite adequate antiviral therapy and administration of the shingles vaccine.

Topical 15% Paromomycin-Aquaphilic Effective For New World Leishmaniasis
Treatment for cutaneous leishmaniasis caused by Leishmania braziliensis, using 15% paromomycin-Aquaphilic, was superior to a negative vehicle control.

Relapse-Free Cure From MDR-TB Higher Than Anticipated
The frequency of relapse-free cure from multidrug-resistant tuberculosis is higher than previously anticipated.

Similar Safety and Efficacy for Rifampin vs Isoniazid in Children, Adolescents
For children younger than 18 years, 4 months of rifampin to treat latent Mycobacterium tuberculosis had similar rates of safety and efficacy and higher rates of adherence compared with 9 months of isoniazid.

AHA Issues Scientific Statement on Managing Chagas Cardiomyopathy
The most common findings in patients with Chagas cardiomyopathy include cardiac rhythm abnormalities, myocardial abnormalities, aneurysms, and thromboembolism.

Is Short-Course Antibiotic Treatment for CAP Effective?
To investigate what impact antibiotic treatment duration has on CAP outcomes, researchers from the Warren Alpert Medical School of Brown University conducted a search of various databases for studies comparing the safety and efficacy of treatment regimens lasting ≤6 days (short) and ≥7 days (long).

FDA Strengthens Warnings for Fluoroquinolone Antibiotics
The labeling changes are based on a review of postmarketing adverse event reports found in the FDA Adverse Event Reporting System (FAERS) database and published medical literature.

FDA Approves Plazomicin for Complicated Urinary Tract Infections
Zemdri carries a Boxed Warning describing reports of nephrotoxicity, ototoxicity, and neuromuscular blockade, as well as fetal harm if administered during pregnancy.

Potential Significant Toxicity With Methotrexate, Trimethoprim-Sulfamethoxazole Combination
The case involved a 68-year-old female patient with rheumatoid arthritis on methotrexate 10mg weekly who presented to the emergency department with complaints of lethargy and weakness after being prescribed a 2-week course of TS for a bacterial skin infection.

FDA Approves New Treatment for Onchocerciasis
Moxidectin, a macrocyclic lactone, is an anthelmintic drug that selectively binds to the parasite's glutamate-gated chloride ion channels.
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