Bowel Cleansers

BOWEL CLEANSERS
Generic Strength Brand Form Usual Dose
HYPEROSMOTICS
monobasic sodium phosphate 19g/
 
118mL
Fleet Enema OTC enema1 Adults: 1 enema rectally daily; may use up to 7 days. Results usually within 1−5min; reevaluate if no relief after 7 days.
Children: Use other forms.
dibasic sodium phosphate 7g/
 
118mL
monobasic sodium phosphate 19g/
 
197mL
Fleet Enema Extra
dibasic sodium phosphate 7g/
 
197mL
ISOSMOTICS
polyethylene 
glycol 3350
60g/L CoLyte w. Flavor Packs Rx pwd for reconsti
tution (add 1 flavor pack before reconsti
tution)
Adults: After fasting for 3−4hrs, 240mL orally every 10min or 20−30mL/min by NG tube until fecal discharge is clear. Usual dose 3−4L. Only clear liqs until exam.
Children: Not recommended.
sodium chloride 1.46g/L
potassium chloride 0.745g/L
sodium bicarbonate 1.68g/L
sodium sulfate 5.68g/L
polyethylene glycol 3350 227.1g/
 
4L
GoLYTELY Rx pwd for reconsti
tution
Adults: May consume water or clear liquids during and after completion of bowel prep up until 2hrs before procedure. Drink 240mL every 10min or 20−30mL/min by NG tube until rectal effluent is clear or 1 gal consumed.
Children: Not established.
sodium chloride 5.53g/4L
potassium chloride 2.82g/4L
sodium bicarbonate 6.36g/4L
sodium sulfate 21.5g/4L
polyethylene glycol 3350 420g/4L TriLyte w. Flavor Packs Rx pwd for reconsti
tution (add 1 flavor pack before reconsti
tution)
Adults: After fasting for 3−4hrs, 240mL orally every 10min or 20−30mL/min by NG tube until rectal discharge is clear or 4L consumed.
Children: <6mos: not recommended. ≥6mos: No solid food for at least 2hrs, then 25mL/kg/hr orally or by NG tube until rectal discharge is clear or 4L consumed.
Both: May interrupt if severe GI disturbances occur.
sodium chloride 11.2g/4L
potassium chloride 1.48g/4L
sodium bicarbonate 5.72g/4L
OSMOTICS
polyethylene glycol 3350 200g/2L MoviPrep Rx pwd for reconsti
tution2
≥18yrs: No solid food from start of prep. No clear liq at least 2hrs before colonoscopy. Both regimens: start evening before colonoscopy. Split‑dose regimen: drink 240mL every 15min over 1hr until 1L consumed, follow with 480mL of clear liq; in the AM (start ≥3.5hrs before colonoscopy) drink 2nd liter over 1hr, then drink 480mL of clear liq at least 2hrs before colonoscopy. Evening-only regimen: start at least 3.5hrs before bedtime; drink 240mL every 15min over 1hr until 1L consumed, then drink 2nd liter 1.5hrs later over 1hr; in addition, drink 1L of clear liq.
sodium sulfate 15g/2L
sodium chloride 5.38g/2L
potassium chloride 2.03g/2L
ascorbic acid 9.4g/2L
sodium ascorbate 11.8g/2L
polyethylene glycol 3350 420g/4L NuLYTELY Rx pwd for reconsti
tution
Adults: 240mL orally every 10min or 20−30mL/min by NG tube until rectal effluent is clear or 4L consumed.
Children: <6mos: not recommended. ≥6mos: 25mL/kg/hr orally or by NG tube until rectal effluent is clear or 4L consumed.
Both: May consume water or clear liq during and after completion of bowel prep up until 2hrs before procedure.
sodium bicarbonate 5.72g/4L
sodium chloride 11.2g/4L
potassium chloride 1.4g/4L
sodium phosphate (as monobasic monohydrate and dibasic anhydrous) 1.5g OsmoPrep Rx tabs ≥18yrs: Evening before colonoscopy: 4 tabs with 8oz of clear liq every 15mins for a total of 20 tabs; repeat on day of colonoscopy 3−5hrs before procedure for a total of 12 tabs. Wait 7 days before retreating.
<18yrs: Not recommended.
polyethylene glycol 3350 140g/32oz Plenvu Rx pwd for reconsti
tution
Adults: Two-day regimen: start the evening before colonoscopy, drink 480mL over 30mins, follow with 480mL of clear liquids over next 30mins; in the AM, drink 480mL over 30mins, then drink 480mL of clear liquids over next 30mins. Consume additional water or clear liquids up to 2hrs before colonoscopy. One-day regimen: start the morning of colonoscopy, drink 480mL over 30mins, follow with 480mL of clear liquids over next 30mins. At minimum of 2hrs after first dose, drink 480mL over 30mins, follow with 480mL of clear liquids over next 30mins. Consume additional water or clear liquids up to 2hrs before colonoscopy.
Children: Not established.
sodium ascorbate 48.11g/32oz
sodium sulfate 9g/32oz
ascorbic acid 7.54g/32oz
sodium chloride 5.2g/32oz
potassium chloride 2.2g/32oz
sodium sulfate 17.5g/6oz Suprep Rx soln for dilution Adults: Start the evening before colonoscopy. Dilute 1 bottle to 16oz with water and drink entire amount. Drink 32oz of water over the next hour. Next morning: repeat using the second bottle. Complete prep at least 2hrs before colonoscopy.
Children: Not established.
potassium sulfate 3.13g/6oz
magnesium sulfate 1.6g/6oz
STIMULANTS
bisacodyl 10mg/30mL Fleet Bisacodyl Enema OTC enema1 Adults: 1 enema rectally daily. Results usually within 5–20min; reevaluate if ineffective.
Children: Not recommended.
STIMULANT + OSMOTIC LAXATIVE
sodium picosulfate 10mg Clenpiq Rx oral soln Adults and Children: <9yrs: not established.
≥9yrs:
Split-Dose regimen (preferred): Take 1st dose evening before colonoscopy followed by five 8oz cups of clear liquids within 5hrs and before bed. Take 2nd dose, the next day approx. 5hrs before colonoscopy followed by at least three 8oz cups of clear liquids, ≥2hrs before procedure. Day-Before regimen (alternative): Take 1st dose in the afternoon or early evening before colonoscopy followed by five 8oz cups of clear liquids within 5hrs and before the next dose. Take 2nd dose approx. 6hrs later in the evening, the night before colonoscopy followed by three 8oz cups of clear liquids within 5hrs and before bed.
magnesium oxide 3.5g
anhydrous citric acid 12g
sodium picosulfate 10mg/pkt Prepopik Rx pwd for reconsti
tution
magnesium oxide 3.5g/pkt
anhydrous citric acid 12g/pkt
NOTES

Key: e‑c = enteric-coated; del‑rel = delayed-release; pwd = powder; supp = suppository

1latex free, contains sodium 4.4g/enema

2contains phenylalanine 131mg/treatment

Not an inclusive list of medications and/or official indications. Please see drug monograph at www.eMPR.com and/or contact company for full drug labeling.

(Rev. 8/2019)

This article originally appeared on MPR