Urinary Tract Infection

Hospital Infections Increase 30-Day Readmission Rates in Patients With Stroke

Hospital Infections Increase 30-Day Readmission Rates in Patients With Stroke

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Investigators examined the effect of common infections such as urinary tract infections, sepsis, and pneumonia on >300,000 patients with ischemic stroke.

Rapid Antimicrobial Susceptibility Testing on Urine Directly Accelerates Results

Rapid Antimicrobial Susceptibility Testing on Urine Directly Accelerates Results

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Rapid antimicrobial susceptibility testing by disc diffusion performed directly on urine samples shows less delay than standard method for diagnosis of UTI.

SGLT2 Inhibitors and Urinary Tract Infections: What's the Link?

SGLT2 Inhibitors and Urinary Tract Infections: What's the Link?

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For this study, the authors identified randomized controlled trials that compared SGLT2 inhibitors with placebo, no treatment, or another antidiabetic agent and reported on UTI outcome.

Cefiderocol Noninferior to Imipenem-Cilastatin in Those at High Risk for Multidrug Resistance UTI

Cefiderocol Noninferior to Imipenem-Cilastatin in Those at High Risk for Multidrug Resistance UTI

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Cefiderocol was noninferior to imipenem-cilastatin in patients with complicated UTI who were at risk for multidrug-resistant infections.

Antibiotic-Resistant Enterobacteriaceae Tied to Clinical Failure in UTI

Antibiotic-Resistant Enterobacteriaceae Tied to Clinical Failure in UTI

Poor clinical outcomes linked to extended spectrum cephalosporin-resistant Enterobacteriaceae.

Prophylaxis With TMP-SMX Did Not Alter Risk for Non-UTI Infections

Prophylaxis With TMP-SMX Did Not Alter Risk for Non-UTI Infections

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Daily prophylaxis with TMP-SMX was not associated with change in risk for skin and soft tissue or sino-pulmonary infections, or pharyngitis in children.

Shorter Course Antibiotics May Be Effective for Pediatric Urinary Tract Infections

Shorter Course Antibiotics May Be Effective for Pediatric Urinary Tract Infections

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Rates of urinary tract infection recurrence after antibiotic depletion did not differ significantly between treatment durations of 7 days, 10 days, and 14 days.

Increasing Water Intake Can Reduce Cystitis Recurrence

Increasing Water Intake Can Reduce Cystitis Recurrence

For women at high risk for recurrence, increasing water intake can prevent recurrence.

High Susceptibility Antibiotics Reduce Readmission Rates for Urinary Tract Infections

High Susceptibility Antibiotics Reduce Readmission Rates for Urinary Tract Infections

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The use of a moderate to low susceptibility antibiotic to treat a urinary tract infection [UTI] may result in a 1.74-fold increase in the odds of an emergency department readmission within 30 days for another UTI.

High Dose Pivmecillinam Effective for UTIs Caused by Resistant <i>Escherichia coli</i>

High Dose Pivmecillinam Effective for UTIs Caused by Resistant Escherichia coli

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Pivmecillinam treatment for community-acquired urinary tract infections (UTIs) caused by ESBL-producing Escherichia coli is a reasonable option.

Prevalence of Resistant Urinary Tract Infections Outpacing Antimicrobial Treatment

Prevalence of Resistant Urinary Tract Infections Outpacing Antimicrobial Treatment

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Approximately 6% of all patients presenting at an emergency department during a one year period with a UTI were diagnosed with an ESBL-producing Enterobacteriaceae infection.

Zemdri Now Available for the Treatment of Complicated UTI, Pyelonephritis

Zemdri Now Available for the Treatment of Complicated UTI, Pyelonephritis

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Zemdri carries a Boxed Warning describing reports of nephrotoxicity, ototoxicity, and neuromuscular blockade, as well as fetal harm if administered during pregnancy.

Newborn Circumcision Associated With Lower UTI Rate in Infants With Hydronephrosis

Newborn Circumcision Associated With Lower UTI Rate in Infants With Hydronephrosis

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Circumcision was associated with decreased risk of UTI in boys with hydronephrosis.

FDA Approves Plazomicin for Complicated Urinary Tract Infections

FDA Approves Plazomicin for Complicated Urinary Tract Infections

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Zemdri carries a Boxed Warning describing reports of nephrotoxicity, ototoxicity, and neuromuscular blockade, as well as fetal harm if administered during pregnancy.

Ibuprofen Inferior to Pivmecillinam for Uncomplicated UTI in Women

Ibuprofen Inferior to Pivmecillinam for Uncomplicated UTI in Women

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A study evaluated whether uncomplicated UTIs in women could be treated without antibiotics.

UTI Treatment Success in Women Greater With Nitrofurantoin vs Fosfomycin

UTI Treatment Success in Women Greater With Nitrofurantoin vs Fosfomycin

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Five-day nitrofurantoin may be a better alternative than single-dose fosfomycin for treating uncomplicated UTI in women.

FDA Panel Votes on Plazomicin for Complicated UTI, Bloodstream Infections

FDA Panel Votes on Plazomicin for Complicated UTI, Bloodstream Infections

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The Committee voted unanimously (15-0) that substantial evidence on the safety and efficacy of plazomicin was presented for the treatment of cUTI but voted against its use (4-11) for the treatment of bloodstream infections in patients with limited or no treatment options.

UTICalc: A New Calculator for Estimating the Probability of UTI in Children

UTICalc: A New Calculator for Estimating the Probability of UTI in Children

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The UTICalc calculator can be used to guide testing and treatment in children with suspected urinary tract infection.

Adverse Outcome Risks With Trimethoprim After UTI in Older Adults

Adverse Outcome Risks With Trimethoprim After UTI in Older Adults

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Results showed that trimethoprim was associated with greater risk for acute kidney injury and hyperkalemia compared with other antibiotic drugs for UTI in older adults.

Inactivity, Prolonged Sitting Tied to Urinary Tract Infections in Men

Inactivity, Prolonged Sitting Tied to Urinary Tract Infections in Men

Result supports the importance of both reducing sitting time and promoting physical activity for preventing lower urinary tract symptoms.

Treating Acute Urinary Tract Infection in Postmenopausal Women

Treating Acute Urinary Tract Infection in Postmenopausal Women

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Expert perspective on management and treatment of acute urinary tract infections in postmenopausal women.

Effectiveness of Meropenem-Vaborbactam for Complicated UTI Treatment

Effectiveness of Meropenem-Vaborbactam for Complicated UTI Treatment

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Evaluating treatment with meropenem/vaborbactam to piperacillin-tazobactam in patients with complicated UTIs.

Cystourethrograms Not Required For All Infant Urinary Tract Infections

Cystourethrograms Not Required For All Infant Urinary Tract Infections

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Investigators assessed the need for conducting routine voiding cystourethrograms in infants diagnosed with urinary tract infection.

Antibiotic Prescribing Habits for UTI in Pregnant Women

Antibiotic Prescribing Habits for UTI in Pregnant Women

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For pregnant women in their first trimester, a 2011 Committee Opinion from the ACOG recommended that sulfonamides and nitrofurantoin may be prescribed only if other antimicrobial therapies are deemed clinically inappropriate.

Antibiotics Frequently Prescribed for Suspected UTI in Nursing Home Residents

Antibiotics Frequently Prescribed for Suspected UTI in Nursing Home Residents

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Five factors were found to be significantly associated with UTI antibiotic use in order of decreasing association: presence of urinary catheter, urinary frequency, fever, new-onset hypotension, and confusion.

Urinalysis Effective for UTI Diagnosis in Younger Febrile Infants

Urinalysis Effective for UTI Diagnosis in Younger Febrile Infants

For febrile infants age 60 days and younger, urinalysis is highly sensitive and specific for diagnosing UTIs.

Human Rhinovirus in Febrile Infants Does Not Alter UTI Risk

Human Rhinovirus in Febrile Infants Does Not Alter UTI Risk

Human rhinovirus is common in febrile infants, and detection does not alter risk of concomitant UTI.

Reason for Hope: Promising Gram-Negative Infection Treatments in the Pipeline

Reason for Hope: Promising Gram-Negative Infection Treatments in the Pipeline

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Dr McKinnell provides a summary of drugs in development for infections caused by Gram-negative bacteria, including carbapenem-resistant Pseudomonas aeruginosa and carbapenem-resistant Enterobacteriaceae.

FDA Clears Diagnostic Urinary Tract Infection Test Strips

FDA Clears Diagnostic Urinary Tract Infection Test Strips

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The Food and Drug Administration has granted clearance for UriVarx urinary tract infection test strips for use in patients with overactive bladder and urinary incontinence.

Priority Review Granted for Treatment of Complicated UTI, Bloodstream Infections

Priority Review Granted for Treatment of Complicated UTI, Bloodstream Infections

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The FDA accepted a new drug application for plazomicin for complicated urinary tract infections.

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