Urinary Tract Infections

Latest News

Oral Beta-Lactams Effective Step-Down Therapy for Bacteremic UTI

By

Zahra Masoud

Study authors compared clinical cure in patients with E coli bacteremic UTI who were stepped down to oral beta-lactams compared to oral fluoroquinolones.

CREDIBLE-CR: Cefiderocol Effective for Serious Carbapenem-Resistant Gram-Negative Infections

By

Bradley van Paridon

Study authors assessed the efficacy and safety of cefiderocol vs best available therapy in adults with serious carbapenem-resistant Gram-negative infections.

Tool Could Optimize Antibiotic Prescribing for UTI

Researchers tested a new decision support tool to optimize antibiotic prescribing for uncomplicated urinary tract infection.

Intravesical Phage Therapy May Treat UTI in Men Undergoing TURP

By

Sweta Gupta

Research authors assessed the safety and efficacy of intravesical bacteriophage therapy compared to placebo and current standard of care for the treatment of urinary tract infection in patients undergoing transurethral resection of the prostate.

Protocolized Urine Sampling Reduces Catheter-Associated UTI

By

Zahra Masoud

Investigators sought to determine whether a new protocol for urine sampling and testing lowers rates of catheter-associated urinary tract infections.

Menopausal Hormonal Therapy May Cut UTI Risk

By

Natasha Persaud

New study is the first focused analysis of bacterial diversity in the urogenital tract of postmenopausal women, according to investigators.

Infection May Increase Risk for Early Stroke Recurrence

By

Amit Akirov, MD

Infection may be associated with an increased risk for early stroke recurrence in hospitalized patients with acute ischemic stroke.

Shorter Antibiotic Treatment Duration Effective for Acute Uncomplicated Cystitis

By

Zahra Masoud

A team of investigators conducted a systematic review and meta-analysis to assess whether a shorter-than-recommended duration of antibiotic treatment can be effective for the management of acute uncomplicated cystitis.

Multiple-Dose Fosfomycin for Complicated UTIs

By

Bradley van Paridon

In cases of complicated urinary tract infections (UTI) treated with multiple-dose fosfomycin, clinical resolution occurred in 2 of 3 treatment episodes.

Novel Cephalosporin Now Available for Treatment of Complicated UTI

By

Diana Ernst, RPh

Fetroja® (cefiderocol) has been made available by Shionogi for the treatment of complicated urinary tract infections (cUTI), including pyelonephritis caused by the following susceptible Gram-negative microorganisms: Escherichia coli, Klebsiella pneumoniae, Proteus mirabilis, Pseudomonas aeruginosa, and Enterobacter cloacae complex.

UTI Recurrence in Pediatric Patients: Antibiotic Treatment Duration Examined

By

Cassandra Pardini, PharmD

In pediatric patients, the duration of antibiotic treatment for uncomplicated UTI was not significantly associated with UTI recurrence.

Vegetarian Diet Linked to Lower Risk for Urinary Tract Infection

A vegetarian diet is associated with a reduced risk for urinary tract infection.

Cefiderocol Approved for Complicated UTI in Patients With Limited or No Alternative Treatment Options

By

Diana Ernst, RPh

The FDA has approved Fetroja for the treatment of complicated urinary tract infections.

UTI Antibiotic Use to be Improved in Nursing Homes

By

Zahra Masoud

Enhanced implementation on adoption of evidence-based antibiotic stewardship in nursing homes focused on the recognition and management of UTIs may improve the quality of antibiotic prescription in nursing homes.

Updated Algorithm Improves Specificity of UTI Detection in Patients With Relapsing Multiple Sclerosis

By

Brandon May

With an improved specificity, an updated algorithm for the detection of UTIs in patients with relapsing MS addresses previous issues concerning the unnecessary prescription of antibiotics, whilst improving accuracy and maintaining safety.

Cefoxitin Is Efficacious in Treatment of Febrile Urinary Tract Infection in Men

By

Infectious Disease Advisor Contributing Writer

A high dose and continuous infusion of cefoxitin has been associated with clinical success in treating febrile urinary tract infections in men caused by extended spectrum beta-lactamase–producing E coli.

FDA Panel Votes on Novel Antibiotic for Complicated UTI

By

Diana Ernst, RPh

The FDA’s Antimicrobial Drugs Advisory Committee voted in favor of approval of cefiderocol for the treatment of complicated UTIs including pyelonephritis.

Comparison of Antibiotic Activity in Complicated UTI From Gram-Negative Bacteria

By

Infectious Disease Advisor Contributing Writer

Ceftazidime-avibactam was highly active against a large collection of gram-negative bacteria isolated from patients with complicated urinary tract infections.

USPSTF Urges Asymptomatic Bacteriuria Screening in Pregnancy

No net benefit seen for screening, treatment of asymptomatic bacteriuria for nonpregnant adults

Risk Factors for Community-Acquired UTI With ESBL-Producing E coli in Children

By

Sweta Gupta

Antibiotic use within the previous 3 months and Middle Eastern ethnic background were risk factors for community-acquired urinary tract infection (UTI) caused by extended-spectrum β-lactamase (ESBL)-producing Escherichia coli in children treated at the Children’s Hospital of Michigan, according to study results published in Infectious Diseases. In this single center retrospective study, researchers identified 111 cases…