Vaccines

An Effective Zika Vaccine May Eliminate Prenatal Infections

An Effective Zika Vaccine May Eliminate Prenatal Infections

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A vaccine against Zika virus, once available and effectively deployed, may substantially reduce prenatal infections.

Herpes Zoster in Healthy Children Linked to Varicella-Zoster Vaccination

Herpes Zoster in Healthy Children Linked to Varicella-Zoster Vaccination

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The morphology of the lesions included erythematous papules, pseudovesicles, and plaques, with associated pain in 2 and pruritus in 3 patients; systemic symptoms ranged from none to low‐grade fevers, upper respiratory symptoms, and joint pain.

Increased Risk for Acute Respiratory Illness Following Influenza Vaccine in Children

Increased Risk for Acute Respiratory Illness Following Influenza Vaccine in Children

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Among children there was an increased risk for acute respiratory illness caused by noninfluenza respiratory pathogens following influenza vaccination compared to unvaccinated children during the same period.

A Zika vaccine could virtually eliminate prenatal infections

A Zika virus vaccine shown to be of moderate to high efficacy in eliminating prenatal infections provides 90% coverage.

Improving Efforts to Prepare for Influenza Epidemics

Improving Efforts to Prepare for Influenza Epidemics

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Although substantial emphasis is placed on vaccinations in considering how to limit the spread of influenza, simple hygienic methods have been found to be the most effective and should be more widely supported.

Findings Support Nonavalent HPV Vaccine Use in Women With HIV

Findings Support Nonavalent HPV Vaccine Use in Women With HIV

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The HR-HPV types covered by the nonavalent HPV vaccine had similar clearance rates to HR-HPV types not included, and women infected with multiple anogenital HR-HPV types had lower rates of clearance than women infected with only 1 type.

Children With ASD, Younger Siblings Are Undervaccinated

Children With ASD, Younger Siblings Are Undervaccinated

Compared with the general population, children with autism spectrum disorder and their younger siblings are undervaccinated.

MenACWY-TT Vaccine Evaluated in Patients With Anatomic/Functional Asplenia

MenACWY-TT Vaccine Evaluated in Patients With Anatomic/Functional Asplenia

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Study evaluated the immunogenicity and safety of 1 and 2 doses of the quadrivalent meningococcal serogroups A, C, W, Y tetanus toxoid-conjugate vaccine in individuals with functional or anatomic asplenia.

Stronger Recommendations by PCPs for Herpes Zoster Vaccination Needed

Stronger Recommendations by PCPs for Herpes Zoster Vaccination Needed

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From January to March 2017, the researchers distributed a cross-sectional online survey to all physicians in the Division of General Internal Medicine and Clinical Innovation at NYULH, across 5 different practice settings. A total of 138 (out of 530) responded (26%).

Role of Vaccines in the Fight Against Antimicrobial Resistance

Role of Vaccines in the Fight Against Antimicrobial Resistance

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The potential role of vaccinations in combatting antimicrobial resistance (AMR) is currently undervalued. The distribution and development of new vaccines should be priorities in efforts to address the AMR crisis.

Vaccine Lessens Incidence of Herpes Zoster Complications in Immuncompetent Older Adults

Vaccine Lessens Incidence of Herpes Zoster Complications in Immuncompetent Older Adults

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Researchers reviewed clinical trial data to evaluate the efficacy of herpes zoster subunit vaccine in preventing complications, hospitalizations, and deaths.

Recombinant Influenza Vaccine Found to Be Safe in Children

Recombinant Influenza Vaccine Found to Be Safe in Children

Researchers compared the safety and immunogenicity of the quadrivalent, recombinant influenza vaccine vs the inactivated influenza vaccine in children and adolescents 6 to 17 years of age.

Quadrivalent recombinant influenza vaccine noninferior to inactivated vaccine

The quadrivalent recombinant influenza vaccine was noninferior when compared with the quadrivalent inactivated influenza vaccine for immunogenicity.

Prevention of Vaccine Failure in <i>Haemophilus influenzae</i> Type B Vaccines

Prevention of Vaccine Failure in Haemophilus influenzae Type B Vaccines

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Higher serum bactericidal activity following immunization with PRP-CRM197 reflected superior short-term and long-term seroprotective effects compared with immunization with PRP-T.

Oral Bivalent Whole-Cell Cholera Vaccine Efficacy Over 5 Years

Oral Bivalent Whole-Cell Cholera Vaccine Efficacy Over 5 Years

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Researchers found that oral cholera vaccine efficacy was statistically significantly higher when administered to children 5 and older compared with children younger than 5, a difference that had been suspected but not conclusively demonstrated in previous trials.

Influenza Vaccination May Reduce Mortality Risk in Heart Failure

Influenza Vaccination May Reduce Mortality Risk in Heart Failure

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A meta-analysis sought to determine the effect of influenza vaccination on cardiac-related mortality in patients with heart failure.

Rotavirus Vaccines Reduce Hospitalizations of Low Birth Weight Infants

Rotavirus Vaccines Reduce Hospitalizations of Low Birth Weight Infants

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Rotavirus vaccines are effective in reducing rates of acute gastroenteritis and rotavirus hospitalizations among low birth weight and very low birth weight children.

Vaccine-Derived Immune Protection Against Mumps Wanes

Vaccine-Derived Immune Protection Against Mumps Wanes

Vaccine-derived immune protection against mumps wanes on average 27 years after vaccination.

Religious Exemptions vs Mandatory Vaccinations: An Expert Perspective

Religious Exemptions vs Mandatory Vaccinations: An Expert Perspective

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Lawyers make things complicated — including policies requiring mandatory influenza vaccinations for healthcare workers.

HPV Vaccination: Should Adolescents Be Allowed to Give Consent?

HPV Vaccination: Should Adolescents Be Allowed to Give Consent?

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Adolescent consent may help minimize delays in vaccination and reduce the overall incidence of cervical, oropharyngeal, and anal cancers.

Myopericarditis Risk in Adults Following Live Viral Vaccination Rare

Myopericarditis Risk in Adults Following Live Viral Vaccination Rare

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Findings confirm that cardiovascular complications related to commonly-administered, live viral vaccination are rare in adults.

Improving HPV Vaccination Rates via Bundled Intervention

Improving HPV Vaccination Rates via Bundled Intervention

A bundled intervention including communication skills training and performance feedback may improve human papillomavirus vaccination.

Fractional Yellow Fever Vaccine Dose Stimulated Effective Immune Response

Fractional Yellow Fever Vaccine Dose Stimulated Effective Immune Response

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The use of fractional doses of yellow fever vaccine could reduce the amount of yellow fever vaccine for reactive campaigns and provide flexibility in management of global stockpile of yellow fever vaccine when outbreaks occur.

Influenza Risk Not Increased by Statins Following Vaccination

Influenza Risk Not Increased by Statins Following Vaccination

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Treatment with statin medications around the time of influenza vaccination does not significantly affect influenza risk in older adults.

Compliance-linked incentives increase infant immunizations rates in rural India

Infantile immunization rates were higher among children whose caregivers received compliance-linked incentives when compared to those who received only mobile phone reminders and those who received no intervention.

Measles Vaccination After Third Dose of DTP Vaccine May Improve Child Survival

Measles Vaccination After Third Dose of DTP Vaccine May Improve Child Survival

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Measles vaccination, administered in the recommended sequence, is associated with improved child survival and may have contribute to the achievement of Millennium Development Goal 4.

Effect of Vaccine Antigen Exposure in First 23 Months of Life

Effect of Vaccine Antigen Exposure in First 23 Months of Life

The estimated cumulative vaccine antigen exposure through age 23 months does not differ significantly for children with vs those without hospital visits for infectious diseases not targeted by vaccines from age 24 to 47 months.

HPV Vaccine Completion Rates in Adolescents Improve With Physician Communication

HPV Vaccine Completion Rates in Adolescents Improve With Physician Communication

For adolescents, a health care professional HPV vaccine communication intervention is associated with improved HPV vaccine series initiation and completion.

Preventing Hospitalizations in the Elderly: High-Dose vs Standard-Dose Influenza Vaccine

Preventing Hospitalizations in the Elderly: High-Dose vs Standard-Dose Influenza Vaccine

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In protecting senior Veterans Health Administration patients against influenza- or pneumonia-associated hospitalization, high-dose influenza vaccine was more effective than standard-dose vaccine.

Risk of Infant Hospitalizations, Death Not Linked to Maternal Vaccination

Risk of Infant Hospitalizations, Death Not Linked to Maternal Vaccination

Maternal receipt of influenza and tetanus toxoid, reduced diphtheria toxoid, and Tdap vaccines is not associated with infant hospitalization or death.

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