First trimester treatment for malaria could change with the results of 1 of the most robust meta-analyses to date that compared artemisinin-based therapy vs quinine.
A 15-year-old African American girl is admitted to the emergency department complaining of fever, vomiting, headache, back pain, and chills.
Women in the United States with uncomplicated malaria during the first trimester of pregnancy should be treated with the currently recommended options of either mefloquine or quinine plus clindamycin. However, when neither of these options is available, artemether-lumefantrine should be considered for treatment.
As long-term neurocognitive deficits can occur as a result of severe malaria, researchers assessed the potential neuroprotective effect of inhaled nitric oxide on children with the infection.
Many patients with a previous West Nile virus infection have abnormalities on neurologic examination several years after they were infected.
The FDA has granted accelerated approval for benznidazole as the first US treatment of Chagas disease in children ages 2 to 12 years.
Placental malaria during pregnancy may raise the risk of malaria infection in childhood by promoting maternal microchimerism, in which the fetus acquires noninherited maternal cells during pregnancy. Maternal microchimerism may be the mechanism by which the fetus develops tolerance to malaria antigens, leading to an impaired malaria-specific immune response.
3 IV doses of PfSPZ vaccine conferred protection after immunization against different Pf strains of malaria than the one the vaccine came from.
Investigational vaccine is designed to trigger an immune response to mosquito saliva rather than to a specific virus or parasite carried by mosquitoes.
Blood-donation screening for antibodies to and DNA from B microti was associated with a decrease in the risk of transfusion-transmitted babesiosis.
Children in study were given three doses, but manufacturer now says four doses needed.
A 2015 fatal human rabies case that took weeks to identify in an elderly woman after a bat encounter underscores the need for better public health outreach.
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