Vector-Borne Illness

CDC: First Case of Rat-Borne Andes Virus Diagnosed in the US

CDC: First Case of Rat-Borne Andes Virus Diagnosed in the US

The first confirmed U.S. case of a virus carried by South American rodents occurred earlier this year.

Flea-Borne Typhus Outbreak in Los Angeles County

Flea-Borne Typhus Outbreak in Los Angeles County

An outbreak of flea-borne typhus in Los Angeles County has so far resulted in 57 cases, including 20 in Pasadena and nine in downtown Los Angeles.

CYP2D6 Enzymatic Activity May Increase Primaquine Malaria Treatment Efficacy

CYP2D6 Enzymatic Activity May Increase Primaquine Malaria Treatment Efficacy

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A natural variability of genotype-determined, CYP2D6-dependent metabolism of primaquine phosphate is associated with an increased risk of failure in the treatment of P vivax malaria.

Short Course Primaquine Regimens for <i>P vivax</i> Malaria Improves Treatment Efficacy

Short Course Primaquine Regimens for P vivax Malaria Improves Treatment Efficacy

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Chloroquine with either 7- or 14-day primaquine regimens provided highly effective radical cure of vivax malaria on the Thailand-Myanmar border.

New Q Fever Foci Identified, Including Acute Endocarditis, Lymphadenitis

New Q Fever Foci Identified, Including Acute Endocarditis, Lymphadenitis

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Acute endocarditis, lymphadenitis, and bone marrow involvement in hemophagocytic syndrome have been newly identified as Q fever foci.

Threat of Zika Virus Still Significant in California

Threat of Zika Virus Still Significant in California

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Since 2015, California has seen many travel-related Zika virus cases, and as the population of mosquitos that spread the virus continue to expand across the state, there is a significant risk for new Zika cases.

Permethrin Plus Pyriproxyfen-Treated Bednets Reduce Malaria Transmission

Permethrin Plus Pyriproxyfen-Treated Bednets Reduce Malaria Transmission

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Long-lasting insecticidal nets treated with permethrin plus pyriproxyfen are more effective in preventing clinical malaria compared with standard insecticidal nets.

Dengue Vaccine Presents Solutions and Backlash in Dengue-Endemic Regions

Dengue Vaccine Presents Solutions and Backlash in Dengue-Endemic Regions

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The principles of "trolleyology" can be used to understand hesitancy among certain individuals to vaccinate against the Dengue virus.

Sustained Follow-Up Essential for Infants of Women Exposed to Zika Virus

Sustained Follow-Up Essential for Infants of Women Exposed to Zika Virus

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Approximately 14% of children who were born to mothers with confirmed or possible Zika virus infection during pregnancy were identified during infancy or early childhood as having a Zika-associated birth defect.

Diagnosing Lyme Disease in Children With Neuropsychiatric Illness

Diagnosing Lyme Disease in Children With Neuropsychiatric Illness

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Health professionals from many disciplines need to be able to recognize the clinical presentations, essential diagnostic tests, and treatment approach of Lyme neuroborreliosis.

Lyme-Bearing Ticks More Widespread in US Than Thought

Lyme-Bearing Ticks More Widespread in US Than Thought

Ticks capable of transmitting Lyme disease and other tick-borne illnesses have been identified in dozens of places across the United States where the pests had never previously been recorded.

Single-Dose Krintafel Approved for the Radical Cure of <i>P vivax</i> Malaria

Single-Dose Krintafel Approved for the Radical Cure of P vivax Malaria

The FDA approved Krintafel for the radical cure of Plasmodium vivax malaria in patients ≥16 years old who are receiving appropriate antimalarial therapy for acute P vivax infection.

Tick-Caused Meat Allergy on the Rise in the United States

Tick-Caused Meat Allergy on the Rise in the United States

Red meat allergy caused by a bite from the lone star tick appears to be on the rise in the United States.

Vivax Malaria Relapses Predominantly Delayed by Chloroquine, Prevented by Primaquine

Vivax Malaria Relapses Predominantly Delayed by Chloroquine, Prevented by Primaquine

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The benefits of using slowly eliminated chloroquine vs rapidly eliminated arsenuate anti-malarials were assessed in a 3-way randomized comparison trial.

Lyme Neuroborreliosis: Long-Term Survival and Health Outcomes

Lyme Neuroborreliosis: Long-Term Survival and Health Outcomes

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Lyme neuroborreliosis diagnosis had no substantial effect on long-term survival, health, or educational/social functioning yet may be associated with an increased risk of hematologic and nonmelanoma skin cancers.

Malaria Therapy During Pregnancy Needs a Translational Booster

Malaria Therapy During Pregnancy Needs a Translational Booster

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First trimester treatment for malaria could change with the results of 1 of the most robust meta-analyses to date that compared artemisinin-based therapy vs quinine.

Case Study: Middle-Aged Man With a Syncopal Episode

Case Study: Middle-Aged Man With a Syncopal Episode

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A middle-aged man presents to the emergency department with a complete heart block, dizziness, fatigue and a recent syncopal episode after camping.

Major Advances on Horizon for Tick-Borne Disease Testing

Major Advances on Horizon for Tick-Borne Disease Testing

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Prompt diagnosis of tick-borne diseases is essential but testing methods have been imprecise. Learn about some recent testing advances for Lyme disease and other tick-borne illnesses.

Fractional Yellow Fever Vaccine Dose Stimulated Effective Immune Response

Fractional Yellow Fever Vaccine Dose Stimulated Effective Immune Response

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The use of fractional doses of yellow fever vaccine could reduce the amount of yellow fever vaccine for reactive campaigns and provide flexibility in management of global stockpile of yellow fever vaccine when outbreaks occur.

FDA Approves Blood Screens for Tickborne Parasite

FDA Approves Blood Screens for Tickborne Parasite

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Babesia parasites are transmitted by common deer ticks, with approximately 1000 to 2000 cases reported each year primarily in Northeastern and Midwestern states.

A New Generation of Challenges for the Traditional Yellow Fever Vaccine

A New Generation of Challenges for the Traditional Yellow Fever Vaccine

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There is no cure or even effective antiviral therapy for yellow fever. Vaccination remains the sole route for preventing mortality from the disease, and WHO projections have already pointed to a significant global shortage.

FDA Grants Orphan Drug Designation for Novel Malaria Drug

FDA Grants Orphan Drug Designation for Novel Malaria Drug

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The FDA granted orphan drug designation to an investigational treatment for malaria.

Mass Drug Administration Can Reduce Short-term Malaria Transmission

Mass Drug Administration Can Reduce Short-term Malaria Transmission

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Mass drug administration has been proposed as a method to eradicate Plasmodium falciparum malaria.

Tick-Born Diseases May Be on the Rise This Season

Tick-Born Diseases May Be on the Rise This Season

According to a national poll, few Americans are aware of the upswing in the tick population this summer.

 Lyme Disease Vaccination Gets Fast Track Designation

Lyme Disease Vaccination Gets Fast Track Designation

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The FDA has given Fast Track designation to Valneva's Lyme disease vaccine candidate.

Treatments for Chronic Lyme Disease Can Carry Serious Risks

Treatments for Chronic Lyme Disease Can Carry Serious Risks

Serious bacterial infections have been documented during Lyme Disease treatment in some patients.

No Elevated Malformations Risk, Low Birth Weight With Maternal Dengue

No Elevated Malformations Risk, Low Birth Weight With Maternal Dengue

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Epidemiological study finds reassuring outcomes for Brazilian babies born to mothers with symptomatic dengue during pregnancy.

Diagnosing Lyme Arthritis in Children

Diagnosing Lyme Arthritis in Children

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Children are among the most susceptible to Lyme disease, and in many, joint inflammation may be the first symptom.

Lyme and Other Tickborne Diseases: Tips for Prevention

Lyme and Other Tickborne Diseases: Tips for Prevention

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The US Centers for Disease Control and Prevention released a toolkit to help individuals protect themselves from Lyme and other tickborne diseases.

Chagas Disease: A Major Public Health Challenge in the US

Chagas Disease: A Major Public Health Challenge in the US

Without treatment, many patients with Chagas disease are at risk of a 'silent death' due to heart failure.

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