Zika Virus

CDC Reports Increase in Birth Defects Potentially Linked to Zika

CDC Reports Increase in Birth Defects Potentially Linked to Zika

There was an increase in the number of birth defects potentially related to Zika virus infection from the first half of 2016 to the second half of 2016.

Evidence of Postnatal Zika Virus Transmission From Breast Milk

Evidence of Postnatal Zika Virus Transmission From Breast Milk

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Although Zika virus is known to be transmitted by mosquitos, sexual contact, blood transfusion, or laboratory exposure, there is also evidence supporting maternal transmission to infants via breastfeeding, delivery, or close contact.

Ongoing Challenges With Severe Congenital Zika Virus

Ongoing Challenges With Severe Congenital Zika Virus

Severe functional limitations are reported among children with microcephaly and laboratory evidence of Zika virus infection in infancy.

Flaviviruses Related to Zika May Cause Congenital Infection

Flaviviruses Related to Zika May Cause Congenital Infection

Emerging neurotropic flaviviruses related to Zika virus may share Zika virus' capacity for transplacental transmission.

Zika Virus Vaccine Progresses Into Phase 1 Clinical Trial

Zika Virus Vaccine Progresses Into Phase 1 Clinical Trial

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An investigational Zika virus vaccine was granted Fast Track designation by the FDA.

Hepatitis C Drug Effective Against Zika Virus in Preclinical Trial

Hepatitis C Drug Effective Against Zika Virus in Preclinical Trial

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The hepatitis C treatment, sofosbuvir was found to be effective against Zika virus in a preclinical trial.

Microcephaly rates elevated in Brazil prior to Zika virus epidemic

Microcephaly was associated with lack of maternal schooling, living without a partner, smoking during pregnancy, intrauterine growth restriction, vaginal delivery, and the pregnancy being the mother's first.

Safety, Efficacy of 2 Zika Virus Vaccine Trials Reported

Safety, Efficacy of 2 Zika Virus Vaccine Trials Reported

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Two trials assessing different vaccination schedules and delivery methods for Zika virus vaccine reveal the vaccines to be safe, well tolerated, and immunogenic.

Epidemiology of Pediatric Zika Virus Infection in the United States

Epidemiology of Pediatric Zika Virus Infection in the United States

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Majority of children presented with only 2 of 4 main symptoms (fever, maculopapular rash, conjunctivitis, and/or arthralgia).

Zika Virus Persists in Tears of Convalescent Patients

Zika Virus Persists in Tears of Convalescent Patients

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Although detection of Zika virus from conjunctiva has been previously reported, presence of Zika virus RNA in conjunctiva at the late convalescent phase of the disease was not known.

Growing Body of Evidence Links Zika Virus With Guillain-Barré Syndrome

Growing Body of Evidence Links Zika Virus With Guillain-Barré Syndrome

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Evidence suggests a link between the Zika virus infection and Guillain-Barré Syndrome.

Zika Virus Preferentially Infects, Kills Glioblastoma Stem Cells

Zika Virus Preferentially Infects, Kills Glioblastoma Stem Cells

The Zika virus preferentially targets glioblastoma stem cells.

CDC Guidance Update for Possible Congenital Zika Infection

CDC Guidance Update for Possible Congenital Zika Infection

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This updated interim guidance is based on current, limited data about Zika virus infection, and reflects the information available as of September 2017.

Rapid Antigen Test Differentiates Zika and Dengue Cases

Rapid Antigen Test Differentiates Zika and Dengue Cases

A rapid immunochromatography approach can differentiate dengue and Zika virus cases

Zika Infection May Lead to High Risk of Neurologic Complications

Zika Infection May Lead to High Risk of Neurologic Complications

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The Zika virus may be associated with a high risk for neurologic complications in affected adults.

Breadth of Viruses Detectable in Semen Examined

Breadth of Viruses Detectable in Semen Examined

A new research letter claims that 27 viruses can be found in human semen.

Single Mutation Contributes to Fetal Microcephaly in Zika Virus

Single Mutation Contributes to Fetal Microcephaly in Zika Virus

A single serine to glutamin substitution (S139N) in the viral polyprotein substantially increased Zika virus infectivity in both human and mouse neural progenitor cells.

Safety, Immunogenicity of Investigational Zika Vaccine Examined

Safety, Immunogenicity of Investigational Zika Vaccine Examined

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Volunteer participants received either 1 mg or 2 mg doses of the GLS-5700 vaccine over 12 weeks.

Congenital Zika, Cobalamin C Deficiency: Retinal Changes Evaluated With SD-OCT

Congenital Zika, Cobalamin C Deficiency: Retinal Changes Evaluated With SD-OCT

Retinal maldevelopment associated with congenital Zika syndrome is similar to the maldevelopment seen with cobalamin C deficiency.

Zika Virus Skews Immunosuppression During Pregnancy, Inducing Rapid Viremia

Zika Virus Skews Immunosuppression During Pregnancy, Inducing Rapid Viremia

The Zika virus thrives in pregnant women by suppressing their already dampened immune systems and running roughshod over their body's natural defenses.

Detection of Zika Virus RNA in Semen

Detection of Zika Virus RNA in Semen

The Zika virus might not last in the semen of infected men as long as previously thought.

Low Risk of Oropharangeal Zika Virus Transmission in Monkeys

Low Risk of Oropharangeal Zika Virus Transmission in Monkeys

Zika virus doesn't appear to be transmitted through saliva in rhesus monkeys.

FDA Issues Emergency Use Authorization for Multiplex Zika Virus Test

FDA Issues Emergency Use Authorization for Multiplex Zika Virus Test

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The FDA issued an Emergency Use Authorization for the Center for Infection and Immunity-ArboViroPlex rRT-PCR Test for Zika virus detection.

New Vaccines May Protect Fetuses Against Zika Virus Infection

New Vaccines May Protect Fetuses Against Zika Virus Infection

Two experimental vaccines may help protect fetuses against the Zika virus.

Eye Abnormalities May Be First Sign of Congenital Zika Virus Infection

Eye Abnormalities May Be First Sign of Congenital Zika Virus Infection

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Infants exposed to the Zika virus in utero should have their eyes examined for possible virus-related abnormalities.

Can Testing Placental Tissue Confirm Zika Infection?

Can Testing Placental Tissue Confirm Zika Infection?

Zika infection can be ruled out or confirmed by testing fetal and placental tissue according to a study published in Morbidity and Mortality Weekly Report.

CDC: Increase in Number of Counties With Zika-Carrying Mosquitoes

CDC: Increase in Number of Counties With Zika-Carrying Mosquitoes

The number of US counties with Zika-carrying mosquitoes is up.

Rate of Birth Defects Nearly 5% With Zika Confirmed Pregnancies

Rate of Birth Defects Nearly 5% With Zika Confirmed Pregnancies

About 1 in 20 women in the US territories who were infected with Zika during pregnancy had babies with possible Zika-associated birth defects.

At Least 4 Different Introductions of Zika Lead to Outbreak in Florida

At Least 4 Different Introductions of Zika Lead to Outbreak in Florida

Research shows the 2016 Zika outbreak in Florida was linked to 4 separate events that introduced and spread the virus.

New Rapid, Low-Cost Test for Zika Virus Surveillance

New Rapid, Low-Cost Test for Zika Virus Surveillance

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A new rapid, low-cost test may enable on-site detection of Zika virus in mosquitoes and human blood and semen, allowing for more efficient disease surveillance and diagnosis.

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