Zika Virus

Screening Blood Donations for Zika Virus Is Costly With Low Yield

Screening Blood Donations for Zika Virus Is Costly With Low Yield

Screening blood donations for Zika virus in the United States is costly with low yield.

Vector-Borne Diseases Up More Than 2-Fold From 2004 to 2016

Vector-Borne Diseases Up More Than 2-Fold From 2004 to 2016

Vector-borne diseases represent an increasing problem in the United States, with a more than 2-fold increase in the number of annual reports from 2004 to 2016.

Zika Virus RNA Often Identified in Semen of Men With Symptomatic Infection

Zika Virus RNA Often Identified in Semen of Men With Symptomatic Infection

Zika virus RNA is frequently present in the semen of men with symptomatic ZIKV infection and can persist for over 6 months.

Pregnancy May Be Independently Associated With Prolonged Detection of Zika Virus RNA

Pregnancy May Be Independently Associated With Prolonged Detection of Zika Virus RNA

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Pregnant women may have about a 3-fold longer estimated median detection window for Zika virus RNA in serum.

An Effective Zika Vaccine May Eliminate Prenatal Infections

An Effective Zika Vaccine May Eliminate Prenatal Infections

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A vaccine against Zika virus, once available and effectively deployed, may substantially reduce prenatal infections.

A Zika vaccine could virtually eliminate prenatal infections

A Zika virus vaccine shown to be of moderate to high efficacy in eliminating prenatal infections provides 90% coverage.

Rate of Birth Defects in Pregnant Women With Confirmed Zika Virus Infection

Rate of Birth Defects in Pregnant Women With Confirmed Zika Virus Infection

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Researchers estimated this risk among pregnant women with symptomatic Zika virus infection in French territories in the Americas.

Zika Virus-Associated Neurogenic Bladder Requires Prompt Management

Zika Virus-Associated Neurogenic Bladder Requires Prompt Management

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Prompt identification may help reduce the risk for subsequent renal failure and minimize overall disease burden.

Zika Virus Infection Linked to Uteroplacental Pathology

Zika Virus Infection Linked to Uteroplacental Pathology

Animal model revealed a potential relationship between Zika virus infection and uteroplacental pathology that appears to affect oxygen delivery to the fetus during development.

CDC Reports Number of Noncongenital Zika Virus Cases in the United States

CDC Reports Number of Noncongenital Zika Virus Cases in the United States

A total of 5168 noncongenital Zika virus disease cases were reported from US states and the District of Columbia in 2016.

CDC Reports Increase in Birth Defects Potentially Linked to Zika

CDC Reports Increase in Birth Defects Potentially Linked to Zika

There was an increase in the number of birth defects potentially related to Zika virus infection from the first half of 2016 to the second half of 2016.

Evidence of Postnatal Zika Virus Transmission From Breast Milk

Evidence of Postnatal Zika Virus Transmission From Breast Milk

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Although Zika virus is known to be transmitted by mosquitos, sexual contact, blood transfusion, or laboratory exposure, there is also evidence supporting maternal transmission to infants via breastfeeding, delivery, or close contact.

Ongoing Challenges With Severe Congenital Zika Virus

Ongoing Challenges With Severe Congenital Zika Virus

Severe functional limitations are reported among children with microcephaly and laboratory evidence of Zika virus infection in infancy.

Flaviviruses Related to Zika May Cause Congenital Infection

Flaviviruses Related to Zika May Cause Congenital Infection

Emerging neurotropic flaviviruses related to Zika virus may share Zika virus' capacity for transplacental transmission.

Zika Virus Vaccine Progresses Into Phase 1 Clinical Trial

Zika Virus Vaccine Progresses Into Phase 1 Clinical Trial

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An investigational Zika virus vaccine was granted Fast Track designation by the FDA.

Hepatitis C Drug Effective Against Zika Virus in Preclinical Trial

Hepatitis C Drug Effective Against Zika Virus in Preclinical Trial

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The hepatitis C treatment, sofosbuvir was found to be effective against Zika virus in a preclinical trial.

Microcephaly rates elevated in Brazil prior to Zika virus epidemic

Microcephaly was associated with lack of maternal schooling, living without a partner, smoking during pregnancy, intrauterine growth restriction, vaginal delivery, and the pregnancy being the mother's first.

Safety, Efficacy of 2 Zika Virus Vaccine Trials Reported

Safety, Efficacy of 2 Zika Virus Vaccine Trials Reported

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Two trials assessing different vaccination schedules and delivery methods for Zika virus vaccine reveal the vaccines to be safe, well tolerated, and immunogenic.

Epidemiology of Pediatric Zika Virus Infection in the United States

Epidemiology of Pediatric Zika Virus Infection in the United States

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Majority of children presented with only 2 of 4 main symptoms (fever, maculopapular rash, conjunctivitis, and/or arthralgia).

Zika Virus Persists in Tears of Convalescent Patients

Zika Virus Persists in Tears of Convalescent Patients

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Although detection of Zika virus from conjunctiva has been previously reported, presence of Zika virus RNA in conjunctiva at the late convalescent phase of the disease was not known.

Growing Body of Evidence Links Zika Virus With Guillain-Barré Syndrome

Growing Body of Evidence Links Zika Virus With Guillain-Barré Syndrome

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Evidence suggests a link between the Zika virus infection and Guillain-Barré Syndrome.

Zika Virus Preferentially Infects, Kills Glioblastoma Stem Cells

Zika Virus Preferentially Infects, Kills Glioblastoma Stem Cells

The Zika virus preferentially targets glioblastoma stem cells.

CDC Guidance Update for Possible Congenital Zika Infection

CDC Guidance Update for Possible Congenital Zika Infection

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This updated interim guidance is based on current, limited data about Zika virus infection, and reflects the information available as of September 2017.

Rapid Antigen Test Differentiates Zika and Dengue Cases

Rapid Antigen Test Differentiates Zika and Dengue Cases

A rapid immunochromatography approach can differentiate dengue and Zika virus cases

Zika Infection May Lead to High Risk of Neurologic Complications

Zika Infection May Lead to High Risk of Neurologic Complications

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The Zika virus may be associated with a high risk for neurologic complications in affected adults.

Breadth of Viruses Detectable in Semen Examined

Breadth of Viruses Detectable in Semen Examined

A new research letter claims that 27 viruses can be found in human semen.

Single Mutation Contributes to Fetal Microcephaly in Zika Virus

Single Mutation Contributes to Fetal Microcephaly in Zika Virus

A single serine to glutamin substitution (S139N) in the viral polyprotein substantially increased Zika virus infectivity in both human and mouse neural progenitor cells.

Safety, Immunogenicity of Investigational Zika Vaccine Examined

Safety, Immunogenicity of Investigational Zika Vaccine Examined

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Volunteer participants received either 1 mg or 2 mg doses of the GLS-5700 vaccine over 12 weeks.

Congenital Zika, Cobalamin C Deficiency: Retinal Changes Evaluated With SD-OCT

Congenital Zika, Cobalamin C Deficiency: Retinal Changes Evaluated With SD-OCT

Retinal maldevelopment associated with congenital Zika syndrome is similar to the maldevelopment seen with cobalamin C deficiency.

Zika Virus Skews Immunosuppression During Pregnancy, Inducing Rapid Viremia

Zika Virus Skews Immunosuppression During Pregnancy, Inducing Rapid Viremia

The Zika virus thrives in pregnant women by suppressing their already dampened immune systems and running roughshod over their body's natural defenses.

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